SCHEMBL980201

SCHEMBL980201

FC(F)(F)c1ccc(Cl)c(Cl)c1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.61
PDE2A O00408 4/20 0.53
RAD51 Q06609 1/20 0.49
ALDH1A1 P00352 3/20 0.47
MAPT P10636 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
NPSR1 Q6W5P4 1/20 0.47
KCNH2 Q12809 6/20 0.45
HTR2A P28223 4/20 0.45
SLC6A4 P31645 4/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
ATM Q13315 1/20 0.44
KIF20B Q96Q89 1/20 0.44
AHR P35869 1/20 0.43
TP53 P04637 1/20 0.43
MCL1 Q07820 1/20 0.43
TMEM97 Q5BJF2 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29402881 1.00 TSHR (0.61) TSHRPDE2ARAD51ALDH1A1MAPT
Ammonia Solution, Strong SCHEMBL28020319 0.97 TSHR (0.58) TSHRPDE2ARAD51ALDH1A1MAPT
SCHEMBL10702885 0.91 TSHR (0.58) TSHRPDE2ARAD51ALDH1A1MAPT
SCHEMBL5406314 0.84 TSHR (0.68) TSHRPDE2ARAD51ALDH1A1MAPT
SCHEMBL27573863 0.82 KCNH2 (0.46) TSHRPDE2ARAD51ALDH1A1MAPT
SCHEMBL19785361 0.82 PDE2A (0.52) TSHRPDE2AALDH1A1MAPTNPSR1
SCHEMBL19785385 0.82 PDE2A (0.47) TSHRPDE2AALDH1A1L3MBTL1MEN1
Potassium Ion SCHEMBL9342787 0.81 PDE2A (0.47) TSHRPDE2ARAD51ALDH1A1MAPT
SCHEMBL1068202 0.80 PDE2A (0.46) TSHRPDE2AALDH1A1MAPTL3MBTL1
SCHEMBL171040 0.80 PDE2A (0.50) TSHRPDE2AALDH1A1L3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 819 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-222534890-U Chlorination device is used in production of 3, 4-dichloro benzotrifluoride 江苏丰华化学工业有限公司 2025-02-28 CN claimed
CN-114292227-B Method for preparing 2-chloro-3-trifluoromethyl pyridine 大连九信精细化工有限公司 2024-12-03 CN claimed
CN-118271215-A Method for synthesizing 2-methylthio-4-trifluoromethyl benzoic acid 江苏中旗科技股份有限公司 2024-07-02 CN claimed
CN-115611717-B Preparation method of polyfluorobenzaldehyde 上海万溯药业有限公司 2024-06-28 CN claimed
CN-117865771-A Synthesis method of 2, 3-dichloro benzotrifluoride 上海泰初化工技术有限公司 2024-04-12 CN claimed
CN-117447328-A Clean production method of oxyfluorfen 首建科技有限公司 2024-01-26 CN claimed
CN-112174826-B Process for synthesizing nitro-diether by adopting narrow-distance parallel plate reactor 西安本清化学技术有限公司 2023-11-24 CN claimed
CN-219964868-U Production system for 3,4-dichloro benzotrifluoride 山东道可化学有限公司 2023-11-07 CN claimed
CN-219922896-U Chlorination device is used in production of 3, 4-dichloro benzotrifluoride 山东道可化学有限公司 2023-10-31 CN claimed
CN-106892792-B Continuous synthesis method and equipment of 3, 4-dichloro benzotrifluoride 山东道可化学有限公司 2023-05-23 CN claimed
US-4485254-A Process for preparing phenoxybenzoic acids ROHM AND HAAS COMPANY (US) 1984-11-27 US claimed
US-4484008-A SOLVENT EXTRACTION WITH WATER AND SEPARATION PPG INDUSTRIES, INC. (US) 1984-11-20 US claimed
US-4450308-A Process for the preparation of trifluoromethylphenyl oxyphenyl ether compounds BAYER AKTIENGESELLSCHAFT (DE) 1984-05-22 US claimed
EP-0033885-B1 PROCESS FOR THE PREPARATION OF (2-CHLORO-4-TRIFLUORMETHYL-PHENYL)-(3-METHOXY-PHENYL)-ETHER BAYER AG (DE) 1984-03-21 EP claimed
US-4424396-A ARYL HALIDE, A-AMINOACID OCCIDENTAL CHEMICAL CORPORATION (US) 1984-01-03 US claimed
US-4405805-A ACIFLUORFEN, XYLENE EXTRACTION RHONE-POULENC, INC. (US) 1983-09-20 US claimed
US-4401623-A Use of calcium chloride to minimize hydrofluoric acid corrosion to glass during the chlorination of 4-chlorobenzotrifluoride RHONE-POULENC AGROCHIMIE (FR) 1983-08-30 US claimed
US-4314078-A Process for preparing 5-(2-chloro-4-trifluoromethylphenoxy)-2-nitro-N-alkanesulphonyl benzamides from a benzoic acid derivative and intermediates ICI AMERICAS INC. (US) 1982-02-02 US claimed
US-4313000-A Process for preparing 5-(2-chloro-4-trifluoromethylphenoxy)-2-nitro-N-alkanesulphonyl benzamides from a toluene derivative and intermediates ICI AMERICAS INC. (US) 1982-01-26 US claimed
US-4289909-A Process for preparing 1-dichloroacyl-4-substituted phenoxy benzene and intermediates therefor CHEVRON RESEARCH (US) 1981-09-15 US claimed