Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28192369 | 0.81 | KMT2A (0.45) | RAB9ANPC1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30845826 | 0.81 | RAB9A (0.46) | RAB9ANPC1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8214376 | 0.81 | RAB9A (0.46) | RAB9ANPC1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30845827 | 0.81 | RAB9A (0.46) | RAB9ANPC1KMT2AKDM4EALDH1A1 | |
| SCHEMBL27792680 | 0.81 | NPC1 (0.51) | RAB9ANPC1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL19545436 | 0.81 | TSHR (0.50) | RAB9ANPC1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL27742395 | 0.80 | NPC1 (0.36) | RAB9ANPC1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1426459 | 0.79 | NPC1 (0.46) | RAB9ANPC1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6237542 | 0.79 | TSHR (0.41) | KMT2AKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL27761128 | 0.79 | ALDH1A1 (0.41) | KMT2AKDM4EALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612156-A1 | ANTI-VIRAL COMPOUNDS | Aligos Therapeutics, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| US-20240287129-A1 | DECARBOXYLATIVE CONJUGATE ADDITIONS AND APPLICATIONS THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY | 2024-08-29 | — | — | US | disclosed |
| US-20240199647-A1 | ANTI-VIRAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-06-20 | — | — | US | disclosed |
| US-11981704-B2 | Decarboxylative conjugate additions and applications thereof | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2024-05-14 | — | — | US | disclosed |
| WO-2024097296-A1 | ANTI-VIRAL COMPOUNDS | ALIGOS THERAPEUTICS, INC. (US) | 2024-05-10 | — | — | WO | disclosed |
| US-20220002342-A1 | DECARBOXYLATIVE CONJUGATE ADDITIONS AND APPLICATIONS THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY | 2022-01-06 | — | — | US | disclosed |
| US-11136349-B2 | Decarboxylative conjugate additions and applications thereof | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2021-10-05 | — | — | US | disclosed |
| CN-110156649-A | A kind of method that silver catalysis prepares 3- phenyl -2- phenyl disulphanes Tri- n -butyltin methacrylate compound | 浙江农林大学暨阳学院 | 2019-08-23 | — | — | CN | disclosed |
| US-20180179248-A1 | DECARBOXYLATIVE CONJUGATE ADDITIONS AND APPLICATIONS THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY | 2018-06-28 | — | — | US | disclosed |
| CN-108025002-A | Six-membered azaheterocyclic containing opioid receptor modulating compounds, methods of use and preparation thereof | 特维娜有限公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-107531660-A | α cinnamide compounds and composition as HDAC8 inhibitor | 福马治疗股份有限公司 | 2018-01-02 | — | — | CN | disclosed |
| WO-2016196931-A1 | DECARBOXYLATIVE CONJUGATE ADDITIONS AND APPLICATIONS THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2016-12-08 | — | — | WO | disclosed |
| CN-103429079-A | Histone deacetylase inhibitors and compositions and methods of use thereof | CHDI FOUNDATION INC | 2013-12-04 | — | — | CN | disclosed |
| US-8293803-B2 | Retinoid compounds and their use | REINNERVATE LIMITED (GB) | 2012-10-23 | — | — | US | disclosed |
| US-20100093088-A1 | RETINOID COMPOUNDS AND THEIR USE | REINNERVATE LIMITED (GB) | 2010-04-15 | — | — | US | disclosed |
| EP-2130908-A2 | Retinoid compounds and their use | REINNERVATE LIMITED (GB) | 2009-12-09 | — | — | EP | disclosed |
| CN-101511993-A | Retinoid compounds and their use | REINNERVATE LTD (GB) | 2009-08-19 | — | — | CN | disclosed |
| EP-2054504-A2 | RETINOID COMPOUNDS AND THEIR USE | REINNERVATE LIMITED (GB) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008025965-A2 | RETINOID COMPOUNDS AND THEIR USE | REINNERVATE LIMITED (GB) | 2008-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180179248-A1 | DECARBOXYLATIVE CONJUGATE ADDITIONS AND APPLICATIONS THEREOF | PTMS, DNPEP, QPCT | RAB9A 2656/4885NPC1 3747/4885KMT2A 3921/4885 |
| US-20220002342-A1 | DECARBOXYLATIVE CONJUGATE ADDITIONS AND APPLICATIONS THEREOF | PTMS, DNPEP, QPCT | RAB9A 2656/4885NPC1 3747/4885KMT2A 3921/4885 |
| US-20240287129-A1 | DECARBOXYLATIVE CONJUGATE ADDITIONS AND APPLICATIONS THEREOF | PTMS, DNPEP, QPCT | RAB9A 2656/4885NPC1 3747/4885KMT2A 3921/4885 |
| US-11981704-B2 | Decarboxylative conjugate additions and applications thereof | PTMS, DNPEP, QPCT | RAB9A 2656/4885NPC1 3747/4885KMT2A 3921/4885 |
| US-11136349-B2 | Decarboxylative conjugate additions and applications thereof | PTMS, DNPEP, QPCT | RAB9A 2656/4885NPC1 3747/4885KMT2A 3921/4885 |
| US-20240199647-A1 | ANTI-VIRAL COMPOUNDS | EIF2AK2, ZC3HAV1, HAVCR2 | RAB9A 347/4885NPC1 34/4885KMT2A 4121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.