SCHEMBL6237542

SCHEMBL6237542

C=C(C(=O)OC)c1ccccc1[O]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
LMNA P02545 1/20 0.41
HSD17B10 Q99714 3/20 0.40
ALDH1A1 P00352 2/20 0.40
CFTR P13569 1/20 0.40
KDM4E B2RXH2 2/20 0.39
POLB P06746 2/20 0.39
ATM Q13315 1/20 0.39
HPGD P15428 1/20 0.37
CTSD P07339 1/20 0.37
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
CA5A P35218 1/20 0.36
MAPT P10636 1/20 0.36
ALOX15 P16050 1/20 0.36
KMT2A Q03164 1/20 0.36
PKM P14618 1/20 0.36
CA12 O43570 1/20 0.35
CA4 P22748 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1426459 0.81 NPC1 (0.46) TSHRLMNAALDH1A1KDM4EPOLB
SCHEMBL27761128 0.81 ALDH1A1 (0.41) TSHRLMNAHSD17B10ALDH1A1CFTR
SCHEMBL27473286 0.81 LMNA (0.60) TSHRLMNAHSD17B10ALDH1A1KDM4E
SCHEMBL28002316 0.79 KMT2A (0.44) TSHRLMNAHSD17B10ALDH1A1CFTR
SCHEMBL3304359 0.79 RAB9A (0.44) TSHRLMNAALDH1A1KDM4EHPGD
SCHEMBL6947591 0.79 ALDH1A1 (0.61) TSHRLMNAHSD17B10ALDH1A1CFTR
SCHEMBL28002678 0.79 POLB (0.50) TSHRALDH1A1POLBHPGDMAPT
SCHEMBL6558492 0.79 CTSD (0.56) TSHRLMNAHSD17B10ALDH1A1HPGD
SCHEMBL12157631 0.79 ALDH1A1 (0.52) ALDH1A1KDM4EHPGDMAPTALOX15
SCHEMBL28297620 0.79 LMNA (0.37) TSHRLMNAHSD17B10ALDH1A1CFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1063252-B1 FLAME-RETARDANT RESIN, COMPOSITION THEREOF, AND PROCESS FOR PRODUCING THE SAME OTSUKA KAGAKU KK (JP) 2005-06-08 EP disclosed
US-6632891-B1 Obtained by an ester exchange reaction between the flame retardant phosphazene and the polycarbonate or polyester resin OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 2003-10-14 US disclosed
EP-1063252-A1 FLAME-RETARDANT RESIN, COMPOSITION THEREOF, AND PROCESS FOR PRODUCING THE SAME OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 2000-12-27 EP disclosed