Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | LMNA | P02545 | 6/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LGMN | Q99538 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31210318 | 1.00 | ALDH1A1 (1.00) | ALDH1A1LMNAKDM4EPKML3MBTL1 | |
| SCHEMBL23850823 | 0.94 | ALDH1A1 (0.89) | ALDH1A1LMNAKDM4EPKML3MBTL1 | |
| Aniline SCHEMBL22169113 | 0.92 | ALDH1A1 (0.84) | ALDH1A1LMNAKDM4EPKML3MBTL1 | |
| SCHEMBL28338201 | 0.88 | ALDH1A1 (0.78) | ALDH1A1LMNAKDM4EPKML3MBTL1 | |
| SCHEMBL20336348 | 0.87 | LMNA (0.77) | ALDH1A1LMNAKDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL330331 | 0.85 | ALDH1A1 (0.73) | ALDH1A1LMNAKDM4EPKML3MBTL1 | |
| SCHEMBL5494223 | 0.85 | ALDH1A1 (0.73) | ALDH1A1LMNAKDM4EPKML3MBTL1 | |
| SCHEMBL23851217 | 0.84 | ALDH1A1 (0.72) | ALDH1A1LMNAKDM4EPKML3MBTL1 | |
| SCHEMBL23429728 | 0.84 | ALDH1A1 (0.72) | ALDH1A1LMNAKDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL5252021 | 0.84 | ALDH1A1 (0.72) | ALDH1A1LMNAKDM4EPKML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109705060-B | Preparation method of N- (2-morpholinyl-5-trifluoromethylphenyl) -2- (3-methylphenoxy) propionamide | 华东理工大学 | 2023-04-14 | — | — | CN | claimed |
| EP-2131656-A2 | PHTHALAZINE DERIVATIVES | Forest Laboratories Holdings Limited (BM) | 2009-12-16 | — | — | EP | claimed |
| US-20080146547-A1 | PHTHALAZINE DERIVATIVES | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-06-19 | — | — | US | claimed |
| WO-2008061108-A2 | PHTHALAZINE DERIVATIVES | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-05-22 | — | — | WO | claimed |
| CN-118973279-A | Solar cell, preparation method thereof, photovoltaic module and photovoltaic system | 天合光能股份有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-109705060-B | Preparation method of N- (2-morpholinyl-5-trifluoromethylphenyl) -2- (3-methylphenoxy) propionamide | 华东理工大学 | 2023-04-14 | — | — | CN | disclosed |
| US-20210161907-A1 | USE OF SMALL MOLECULE FAK ACTIVATORS TO PROMOTE MUCOSAL HEALING | UNIVERSITY OF NORTH DAKOTA | 2021-06-03 | — | — | US | disclosed |
| EP-3345893-B1 | UREA DERIVATIVE AND USE THEREFOR | TORAY INDUSTRIES (JP) | 2019-10-30 | — | — | EP | disclosed |
| EP-3345893-B1 | UREA DERIVATIVE AND USE THEREFOR | TORAY INDUSTRIES (JP) | 2019-10-30 | — | — | EP | disclosed |
| EP-2666481-B9 | Method of regulating phosphorylation of sr protein and antiviral agents comprising sr protein activity regulator as the active ingredient | HAGIWARA MASATOSHI (JP) | 2019-05-22 | — | — | EP | disclosed |
| EP-2666481-B9 | Method of regulating phosphorylation of sr protein and antiviral agents comprising sr protein activity regulator as the active ingredient | HAGIWARA MASATOSHI (JP) | 2019-05-22 | — | — | EP | disclosed |
| US-10280145-B2 | Urea derivative and use therefor | TORAY INDUSTRIES, INC. (JP) | 2019-05-07 | — | — | US | disclosed |
| CN-1057648-A | Therapeutical agent | BOOTS CO PLC (GB) | 1992-01-08 | — | — | CN | disclosed |
| EP-0385038-A1 | Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them | The Boots Company PLC (GB) | 1990-09-05 | — | — | EP | disclosed |
| US-4168151-A | HERBICIDES | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1979-09-18 | — | — | US | disclosed |
| US-4153443-A | HERBICIDES | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1979-05-08 | — | — | US | disclosed |
| US-4133672-A | (Aminophenyl)morpholines and use thereof | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1979-01-09 | — | — | US | disclosed |
| US-4133673-A | HERBICIDES | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1979-01-09 | — | — | US | disclosed |
| US-4123251-A | HERBICIDES | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1978-10-31 | — | — | US | disclosed |
| US-4049422-A | Herbicidal morpholinobenzimidazoles | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1977-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146547-A1 | PHTHALAZINE DERIVATIVES | CDK5, HIPK2, PACSIN2 | ALDH1A1 3613/4885LMNA 3793/4885KDM4E 761/4885 |
| US-10280145-B2 | Urea derivative and use therefor | UTS2R, DDR1, WEE1 | ALDH1A1 1393/4885LMNA 4279/4885KDM4E 3264/4885 |
| US-20210161907-A1 | USE OF SMALL MOLECULE FAK ACTIVATORS TO PROMOTE MUCOSAL HEALING | PTK2, CTTN, TNK2 | ALDH1A1 3526/4885LMNA 3916/4885KDM4E 3883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.