SCHEMBL3305103

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24872449	0.91	TRPV4 (0.61)	TRPV4CYP11B1CYP11B2MAOBMAOA
	SCHEMBL30037290	0.86	IDH1 (0.43)	TRPV4MAOBMAOAIDH1CALM1
	SCHEMBL3512013	0.86	IDH1 (0.43)	TRPV4MAOBMAOAIDH1CALM1
	SCHEMBL17971117	0.84	TRPV4 (0.53)	TRPV4CYP11B1CYP11B2MAOBMAOA
	SCHEMBL12812248	0.83	TRPV4 (0.49)	TRPV4CYP11B1CYP11B2MAOBMAOA
	SCHEMBL7673699	0.81	NR1D1 (0.48)	TRPV4CYP11B1CYP11B2KDM4EHPGD
	SCHEMBL1681134	0.79	MAOB (0.44)	MAOBMAOAIDH1CALM1FNTA
	SCHEMBL16848649	0.78	CYP11B1 (0.50)	TRPV4CYP11B1CYP11B2KCNJ1
	SCHEMBL16922699	0.78	CYP11B1 (0.50)	TRPV4CYP11B1CYP11B2KCNJ1
	SCHEMBL7680189	0.78	L3MBTL1 (0.46)	TRPV4CYP11B1CYP11B2DAOGPR52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.