Sugi Predict

Sugi Predict / Compounds / SCHEMBL330561

SCHEMBL330561

SCHEMBL330561

Nc1cc(Cl)c(Cl)c(Cl)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 8/20 0.65
▸ ALDH1A1 P00352 5/20 0.65
▸ THRB P10828 2/20 0.58
▸ TSHR P16473 5/20 0.50
▸ TP53 P04637 1/20 0.50
▸ HPGD P15428 4/20 0.47
▸ HSD17B10 Q99714 4/20 0.47
▸ CRHBP P24387 1/20 0.47
▸ CRHR2 Q13324 1/20 0.47
▸ GAA P10253 1/20 0.44
▸ CA1 P00915 1/20 0.43
▸ CA2 P00918 1/20 0.43
▸ HTR3E A5X5Y0 1/20 0.42
▸ HTR3B O95264 1/20 0.42
▸ HTR3A P46098 1/20 0.42
▸ HTR3D Q70Z44 1/20 0.42
▸ HTR3C Q8WXA8 1/20 0.42
▸ AHR P35869 4/20 0.41
▸ CASP1 P29466 2/20 0.40
▸ CYP1B1 Q16678 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8840292 0.97 CYP3A4 (0.61) CYP3A4ALDH1A1THRBTSHRTP53
SCHEMBL28421611 0.97 CYP3A4 (0.61) CYP3A4ALDH1A1THRBTSHRTP53
SCHEMBL27522944 0.84 CYP3A4 (0.55) CYP3A4ALDH1A1THRBTSHRTP53
SCHEMBL29675989 0.80 CYP3A4 (0.50) CYP3A4ALDH1A1THRBTSHRTP53
SCHEMBL21050901 0.80 CYP3A4 (0.50) CYP3A4ALDH1A1THRBTSHRTP53
SCHEMBL24622828 0.80 CYP3A4 (0.52) CYP3A4ALDH1A1THRBTSHRTP53
SCHEMBL31246242 0.80 CYP3A4 (0.50) CYP3A4ALDH1A1THRBTSHRTP53
SCHEMBL17964095 0.80 CYP3A4 (0.50) CYP3A4ALDH1A1THRBTSHRTP53
SCHEMBL12908958 0.80 THRB (0.59) CYP3A4ALDH1A1THRBTSHRTP53
SCHEMBL292270 0.79 CYP3A4 (1.00) CYP3A4ALDH1A1THRBTSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 510 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122031492-A Chitin synthetase inhibitor and its preparation and application 中国科学院海洋研究所 2026-05-15 — — CN claimed
CN-117430733-A Bimetallic catalyst based on acylhydrazone pyrene skeleton, and preparation method and application thereof 万华化学集团股份有限公司 2024-01-23 — — CN claimed
CN-114315640-B Stable isotope labeled chlorothalonil and synthesis method thereof 上海安谱实验科技股份有限公司 2023-06-23 — — CN claimed
CN-111362835-B Carbodiimide compound with flame retardant and hydrolysis resistant functions and preparation method thereof 苏州科晟通新材料科技有限公司 2022-08-30 — — CN claimed
CN-114315640-A Stable isotope labeled chlorothalonil and synthesis method thereof 上海安谱实验科技股份有限公司 2022-04-12 — — CN claimed
CN-112851559-A FtsZ and QseC double-target antibacterial molecule and preparation method and application thereof 中国人民解放军空军军医大学 2021-05-28 — — CN claimed
CN-107903269-B Preparation method of anagrelide trichloro derivative 湖北省宏源药业科技股份有限公司 2021-05-04 — — CN claimed
CN-107903269-A A kind of preparation method of three chlorine derivative of anagrelide 湖北省宏源药业科技股份有限公司 2018-04-13 — — CN claimed
US-8916599-B2 1H-benz imidazole-5-carboxamides as anti-inflammatory agents OREXO AB (SE) 2014-12-23 — — US claimed
US-20110312935-A1 1H-Benz Imidazole-5-Carboxamides As Anti-Inflammatory Agents BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2011-12-22 — — US claimed
WO-2010034796-A1 1H-BENZ IMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-04-01 — — WO claimed
US-6372030-B1 INK VEHICLE SELECTED FROM 4-(HEXADECYLAMINO)BENZYLAMINE, N-OCTANOYL-N-METHYL GLUCAMINE, OCTANOIC HYDRAZIDE, 4-HEXADECYL SULFONYL ANILINE, A CONDUCTIVE COMPLEX OF AN AMINE COMPOUND WITH A PHOSPHORUS OR SULFUR-CONTAINING ACID XEROX CORPORATION 2002-04-16 — — US claimed
EP-0319452-B1 Monoazo pigments, process to manufacture them and their use HOECHST AG (DE) 1994-05-18 — — EP claimed
EP-0319452-A2 Monoazo pigments, process to manufacture them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1989-06-07 — — EP claimed
US-4085141-A Process for the preparation of anilines meta-substituted by chlorine BAYER AKTIENGESELLSCHAFT (DT) 1978-04-18 — — US claimed
CN-117428187-B Method for preparing carbon-coated copper by in-situ reduction of polydopamine-like copper oxide, carbon-coated copper and application 深圳大学 2026-05-19 — — CN disclosed
CN-122031492-A Chitin synthetase inhibitor and its preparation and application 中国科学院海洋研究所 2026-05-15 — — CN disclosed
US-3990879-A SUBSTITUTED 1-THIADIAZOLYL-3-ARYL-UREAS ELI LILLY AND COMPANY (US) 1976-11-09 — — US disclosed
US-3975534-A Pharmaceutical compositions useful for treating tick infestation in animals which contain 2-aryliminopyrrolidines or their salts as the active agent BAYER AKTIENGESELLSCHAFT (DT) 1976-08-17 — — US disclosed
US-3965175-A MALONANILIDE SCHERING CORPORATION (US) 1976-06-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110312935-A1 1H-Benz Imidazole-5-Carboxamides As Anti-Inflammatory Agents MAPRE2, MAPRE1, H1-4 CYP3A4 556/4885ALDH1A1 1202/4885THRB 2474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.