Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27294411 | 0.95 | TDP1 (0.54) | NPC1RAB9ATDP1TSHRMAPK1 | |
| SCHEMBL29199338 | 0.87 | ALDH1A1 (0.53) | NPC1RAB9ATDP1TSHRMAPK1 | |
| SCHEMBL8745095 | 0.79 | ALDH1A1 (0.42) | NPC1RAB9ATDP1TSHRMAPK1 | |
| SCHEMBL10345933 | 0.76 | TDP1 (0.63) | NPC1RAB9ATDP1TSHRMAPK1 | |
| SCHEMBL11234922 | 0.75 | MEN1 (0.52) | NPC1RAB9ATDP1TSHRMAPK1 | |
| SCHEMBL11301112 | 0.74 | TDP1 (0.56) | NPC1RAB9ATDP1TSHRMAPK1 | |
| SCHEMBL10346028 | 0.73 | RAB9A (0.56) | NPC1RAB9ATDP1TSHRMAPK1 | |
| SCHEMBL21294030 | 0.73 | NPC1 (0.48) | NPC1RAB9ATDP1TSHRMAPK1 | |
| SCHEMBL29351476 | 0.72 | MEN1 (0.62) | NPC1RAB9ATDP1TSHRMAPK1 | |
| SCHEMBL292217 | 0.72 | MEN1 (0.62) | NPC1RAB9ATDP1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093880-A1 | RECYCLING CLEAVAGE OF POLYURETHANES | PUREC GMBH (DE) | 2010-04-15 | — | — | US | disclosed |
| EP-0279376-B1 | Process for producing polyurea resin | IHARA CHEMICAL IND CO (JP) | 1993-11-03 | — | — | EP | disclosed |
| US-5086153-A | Reacting aromatic polyamine, specific aminobenzoate derivative and polyisocyanate | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1992-02-04 | — | — | US | disclosed |
| US-5039775-A | Process for producing polyurea resin | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-08-13 | — | — | US | disclosed |
| EP-0279376-A2 | Process for producing polyurea resin | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 1988-08-24 | — | — | EP | disclosed |
| US-4327204-A | Process for producing polyurethane elastomer by mixing a hardener composition with an isocyanate composition | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1982-04-27 | — | — | US | disclosed |