Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.76 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.76 |
| ▸ | ACLY | P53396 | 2/20 | 0.62 |
| ▸ | ACACA | Q13085 | 2/20 | 0.62 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.47 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 6/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | CRYAB | P02511 | 2/20 | 0.40 |
| ▸ | CRYAA | P02489 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13642588 | 0.90 | HSD11B1 (0.62) | HSD11B1HSD11B2ACLYACACAPTPN11 | |
| SCHEMBL13642319 | 0.90 | HSD11B1 (0.62) | HSD11B1HSD11B2ACLYACACAPTPN11 | |
| SCHEMBL29510985 | 0.85 | ACLY (0.67) | HSD11B1HSD11B2ACLYACACAPTPN11 | |
| SCHEMBL12634185 | 0.85 | ACLY (0.67) | HSD11B1HSD11B2ACLYACACAPTPN11 | |
| SCHEMBL13420288 | 0.85 | ACLY (0.70) | HSD11B1HSD11B2ACLYACACAPTPN11 | |
| SCHEMBL1878450 | 0.84 | HSD11B1 (0.56) | HSD11B1HSD11B2ACLYACACAPTPN11 | |
| SCHEMBL17599781 | 0.84 | HSD11B1 (0.56) | HSD11B1HSD11B2ACLYACACAPTPN11 | |
| SCHEMBL15662610 | 0.84 | ACLY (0.66) | HSD11B1HSD11B2ACLYACACAPTPN11 | |
| SCHEMBL17057009 | 0.84 | ACLY (0.66) | HSD11B1HSD11B2ACLYACACAPTPN11 | |
| SCHEMBL4232501 | 0.84 | HSD11B1 (0.62) | HSD11B1HSD11B2ACLYACACAPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150004260-A1 | METHODS FOR INHIBITING PROSTATE CANCER BY KINASES AND ANGIOGENESIS INHIBITORY MECHANISMS OF BALL MOSS EXTRACT | UNIVERSITY OF MARYLAND, BALTIMORE | 2015-01-01 | — | — | US | claimed |
| US-8715748-B2 | Methods for inhibiting prostate cancer by kinases and angiogenesis inhibitory mechanisms of ball moss extract | UNIVERSITY OF MARYLAND, BALTIMORE | 2014-05-06 | — | — | US | claimed |
| US-20130323330-A1 | METHODS FOR INHIBITING PROSTATE CANCER BY KINASES AND ANGIOGENESIS INHIBITORY MECHANISMS OF BALL MOSS EXTRACT | UNIVERSITY OF MARYLAND, BALTIMORE | 2013-12-05 | — | — | US | claimed |
| US-9040100-B2 | Methods for inhibiting prostate cancer by kinases and angiogenesis inhibitory mechanisms of ball moss extract | UNIVERSITY OF MARYLAND, BALTIMORE | 2015-05-26 | — | — | US | disclosed |
| US-20150004260-A1 | METHODS FOR INHIBITING PROSTATE CANCER BY KINASES AND ANGIOGENESIS INHIBITORY MECHANISMS OF BALL MOSS EXTRACT | UNIVERSITY OF MARYLAND, BALTIMORE | 2015-01-01 | — | — | US | disclosed |
| US-8715748-B2 | Methods for inhibiting prostate cancer by kinases and angiogenesis inhibitory mechanisms of ball moss extract | UNIVERSITY OF MARYLAND, BALTIMORE | 2014-05-06 | — | — | US | disclosed |
| US-20130323330-A1 | METHODS FOR INHIBITING PROSTATE CANCER BY KINASES AND ANGIOGENESIS INHIBITORY MECHANISMS OF BALL MOSS EXTRACT | UNIVERSITY OF MARYLAND, BALTIMORE | 2013-12-05 | — | — | US | disclosed |
| US-20100098788-A1 | Extracts of Curcuma and Methods of Use Thereof | HERBALSCIENCE GROUP, LLC | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150004260-A1 | METHODS FOR INHIBITING PROSTATE CANCER BY KINASES AND ANGIOGENESIS INHIBITORY MECHANISMS OF BALL MOSS EXTRACT | MAP3K11, MAP3K7, MAP3K1 | HSD11B1 548/4885HSD11B2 644/4885ACLY 1518/4885 |
| US-20130323330-A1 | METHODS FOR INHIBITING PROSTATE CANCER BY KINASES AND ANGIOGENESIS INHIBITORY MECHANISMS OF BALL MOSS EXTRACT | MAP3K11, MAP3K7, MAP3K1 | HSD11B1 548/4885HSD11B2 644/4885ACLY 1518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.