Thioglycolic Acid

Thioglycolic Acid

SCHEMBL330700

CCCSO.O=C(O)CS.O=C(O)CS

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.38
HDAC3 O15379 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
TDP1 Q9NUW8 3/20 0.37
MAPT P10636 2/20 0.35
HSD17B10 Q99714 2/20 0.35
GMNN O75496 1/20 0.35
TP53 P04637 1/20 0.35
POLB P06746 1/20 0.35
THRB P10828 1/20 0.35
CYP2C9 P11712 1/20 0.35
BLM P54132 1/20 0.35
TSHR P16473 5/20 0.33
KMT2A Q03164 2/20 0.33
AKR1B1 P15121 1/20 0.33
PPARG P37231 6/20 0.32
PPARD Q03181 6/20 0.32
PPARA Q07869 6/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mercaptopropionic Acid SCHEMBL331356 0.84 FFAR3 (0.44) FFAR3HDAC3HDAC1HDAC2HDAC8
Thioglycolic Acid SCHEMBL890671 0.83 TSHR (0.36) FFAR3HDAC3HDAC1HDAC2HDAC8
Thioglycolic Acid SCHEMBL28107448 0.83 TSHR (0.36) FFAR3HDAC3HDAC1HDAC2HDAC8
Thioglycolic Acid SCHEMBL18423175 0.81
Thioglycolic Acid SCHEMBL331990 0.81 FFAR3 (0.42) FFAR3HDAC3HDAC1HDAC2HDAC8
Thioglycolic Acid SCHEMBL3284619 0.78
Thioglycolic Acid SCHEMBL476547 0.78 FFAR3 (0.50) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL1548060 0.78
SCHEMBL20474966 0.76 TDP1 (0.34) FFAR3HDAC3HDAC1HDAC2HDAC8
Thioglycolic Acid SCHEMBL331620 0.75 FFAR3 (0.39) FFAR3HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 307 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6391433-B1 None US disclosed
US-12534563-B2 Block copolymer, resin composition, stretch conductor, electronic device, and pressure-sensitive adhesive film ARTIENCE CO., LTD. (JP) 2026-01-27 US disclosed
EP-4620947-A1 ISOCYANATE COMPOSITION, MODIFIED ISOCYANATE, POLYURETHANE RESIN AND OPTICAL MATERIAL Wanhua Chemical Group Co., Ltd. (CN) 2025-09-24 EP disclosed
US-20250197555-A1 ISOCYANATE COMPOSITION, MODIFIED ISOCYANATE, POLYURETHANE RESIN AND OPTICAL MATERIAL WANHUA CHEMICAL GROUP CO., LTD. (CN) 2025-06-19 US disclosed
US-12297301-B2 High-molecular-weight compound and method for producing same, composition and method for producing same, resin composition, additive for lubricating oil, and lubricating oil MITSUBISHI CHEMICAL CORPORATION (JP) 2025-05-13 US disclosed
EP-3483219-B1 TRANSPARENT PLASTIC SUBSTRATE AND PLASTIC LENS HOYA LENS THAILAND LTD (TH) 2024-08-14 EP disclosed
US-12054568-B2 Optical material composition and optical material TOKUYAMA CORPORATION (JP) 2024-08-06 US disclosed
EP-3643735-B1 PHOTOCHROMIC POLYROTAXANE COMPOUND, AND CURABLE COMPOSITION CONTAINING SAID PHOTOCHROMIC POLYROTAXANE COMPOUND TOKUYAMA CORP (JP) 2024-07-31 EP disclosed
US-20240166795-A1 XYLYLENE DIISOCYNATE COMPOSITION, PREPARATION METHOD THEREFOR AND USE THEREOF WANHUA CHEMICAL GROUP CO., LTD. (CN) 2024-05-23 US disclosed
EP-4306509-A1 XYLYLENE DIISOCYNATE COMPOSITION, PREPARATION METHOD THEREFOR AND USE THEREOF Wanhua Chemical Group Co., Ltd (CN) 2024-01-17 EP disclosed
US-5194559-A Reacting compounds containing isocyanate and isothiocyanate groups with polyol and polythiol; colorlrss, transparent MITSUI TOATSU CHEMICALS, INC. (JP) 1993-03-16 US disclosed
EP-0506315-A2 Optical urethane resins and plastic lenses comprising the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-30 EP disclosed
US-5126388-A Sulfur-containing polyurethane or polythiourethane and internal mold release agent MITSUI TOATSU CHEMICALS, INC. (JP) 1992-06-30 US disclosed
US-5084545-A Polythiourethanes for impact strength, lightweight lenses MITSUI TOATSU CHEMICALS, INC. (JP) 1992-01-28 US disclosed
US-5021503-A Polythiourethanes from sulfur-containing aliphatic diisocyanates and polythiols or polyols; colorless MITSUI TOATSU CHEMICALS, INC. (JP) 1991-06-04 US disclosed
US-5013496-A Polyurethane or polythiourethane MITSUI TOATSU CHEMICALS, INC. (JP) 1991-05-07 US disclosed
EP-0351073-A2 Lens comprising a resin having a large refractive index and process for preparing the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-01-17 EP disclosed
EP-0330363-A2 Highly-refractive plastic lens and process for making the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-30 EP disclosed
EP-0329388-A2 Plastic lenses having high-refractive index and process for the preparation thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed
EP-0329387-A2 Plastic lens, and method for its preparation MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534563-B2 Block copolymer, resin composition, stretch conductor, electronic device, and pressure-sensitive adhesive film EPB41, ITGB4, ITGB5 FFAR3 1226/4885HDAC3 4629/4885HDAC1 4404/4885
US-20240166795-A1 XYLYLENE DIISOCYNATE COMPOSITION, PREPARATION METHOD THEREFOR AND USE THEREOF DCXR, NOTUM, FDFT1 FFAR3 1158/4885HDAC3 4623/4885HDAC1 3436/4885
US-20250197555-A1 ISOCYANATE COMPOSITION, MODIFIED ISOCYANATE, POLYURETHANE RESIN AND OPTICAL MATERIAL PUF60, XRCC6, XRCC5 FFAR3 1647/4885HDAC3 2170/4885HDAC1 2599/4885
US-12297301-B2 High-molecular-weight compound and method for producing same, composition and method for producing same, resin composition, additive for lubricating oil, and lubricating oil TMT1A, TST, NOTUM FFAR3 1707/4885HDAC3 4502/4885HDAC1 3680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.