Thioglycolic Acid

Thioglycolic Acid

SCHEMBL331620

CSO.O=C(O)CS.O=C(O)CS

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.39
TSHR P16473 5/20 0.36
HSD17B10 Q99714 2/20 0.36
CYP2D6 P10635 2/20 0.35
CYP2C19 P33261 1/20 0.35
HIF1A Q16665 1/20 0.35
FOLH1 Q04609 1/20 0.35
LMNA P02545 3/20 0.33
RNPEP Q9H4A4 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
ACE P12821 1/20 0.33
LDHA P00338 1/20 0.33
SRR Q9GZT4 1/20 0.33
ALKBH5 Q6P6C2 1/20 0.33
SUCNR1 Q9BXA5 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
SLC15A2 Q16348 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thioglycolic Acid SCHEMBL28080694 1.00
Thioglycolic Acid SCHEMBL331396 0.88 FFAR3 (0.35) FFAR3TSHRHSD17B10CYP2D6CYP2C19
Thioglycolic Acid SCHEMBL18423900 0.88
Thioglycolic Acid SCHEMBL9449577 0.82
Thioglycolic Acid SCHEMBL3079958 0.82
Thioglycolic Acid SCHEMBL874629 0.82
Thioglycolic Acid SCHEMBL21017 0.82
Thioglycolic Acid SCHEMBL134322 0.82 LMNA (0.46) FFAR3TSHRHSD17B10CYP2D6CYP2C19
Thioglycolic Acid SCHEMBL331990 0.81 FFAR3 (0.42) FFAR3TSHRHSD17B10CYP2D6CYP2C19
Thioglycolic Acid SCHEMBL27470848 0.81 FFAR3 (0.35) FFAR3TSHRHSD17B10CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 617 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12275813-B2 Polymerizable composition for optical materials and application of same MITSUI CHEMICALS, INC. (JP) 2025-04-15 US claimed
CN-105992781-B The manufacturing method of optical material 三井化学株式会社 2019-09-24 CN claimed
CN-104755520-B Polymerizable composition, polymerizable composition, optical material and its manufacturing method 三井化学株式会社 2018-10-09 CN claimed
EP-2963457-B1 OPTICAL MATERIAL, COMPOSITION FOR USE THEREIN, AND USE THEREOF MITSUI CHEMICALS INC (JP) 2018-07-11 EP claimed
EP-2921511-B1 POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL AND MANUFACTURING METHOD FOR SAME MITSUI CHEMICALS INC (JP) 2017-11-01 EP claimed
US-9778397-B2 Polymerizable composition, optical material, and manufacturing method of the same MITSUI CHEMICALS, INC. (JP) 2017-10-03 US claimed
US-20150331147-A1 POLYMERIZABLE COMPOSITION, OPTICAL MATERIAL, AND MANUFACTURING METHOD OF THE SAME MITSUI CHEMICALS, INC. (JP) 2015-11-19 US claimed
US-6391433-B1 None US disclosed
WO-2026105643-A1 ISOCYANATE COMPOSITION, POLYMERIZABLE COMPOSITION, RESIN, MOLDED BODY, OPTICAL ELEMENT, AND LENS 三井化学株式会社 2026-05-21 WO disclosed
WO-2026105644-A1 ISOCYANATE COMPOSITION, POLYMERIZABLE COMPOSITION, RESIN, MOLDED BODY, OPTICAL ELEMENT, AND LENS 三井化学株式会社 2026-05-21 WO disclosed
US-12625430-B2 Colored photosensitive resin composition and mutilayer cured film prepared therefrom DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2026-05-12 US disclosed
EP-4725987-A2 XYLYLENE DIISOCYANATE COMPOSITION, POLYMERIZABLE COMPOSITION, RESIN, MOLDED BODY, OPTICAL ELEMENT, AND LENS TECHNICAL FIELD Mitsui Chemicals, Inc. (JP) 2026-04-15 EP disclosed
US-12570864-B2 Storage-stable pigmented formulations containing isocyanate groups and use thereof COVESTRO DEUTSCHLAND AG (DE) 2026-03-10 US disclosed
US-5084545-A Polythiourethanes for impact strength, lightweight lenses MITSUI TOATSU CHEMICALS, INC. (JP) 1992-01-28 US disclosed
US-5021503-A Polythiourethanes from sulfur-containing aliphatic diisocyanates and polythiols or polyols; colorless MITSUI TOATSU CHEMICALS, INC. (JP) 1991-06-04 US disclosed
US-5013496-A Polyurethane or polythiourethane MITSUI TOATSU CHEMICALS, INC. (JP) 1991-05-07 US disclosed
EP-0351073-A2 Lens comprising a resin having a large refractive index and process for preparing the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-01-17 EP disclosed
EP-0330363-A2 Highly-refractive plastic lens and process for making the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-30 EP disclosed
EP-0329387-A2 Plastic lens, and method for its preparation MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed
EP-0329388-A2 Plastic lenses having high-refractive index and process for the preparation thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12625430-B2 Colored photosensitive resin composition and mutilayer cured film prepared therefrom RAD51, SMURF1, SMARCA1 FFAR3 3951/4885TSHR 3022/4885HSD17B10 4667/4885
US-12570864-B2 Storage-stable pigmented formulations containing isocyanate groups and use thereof RB1, ALDH1A2, IDH3A FFAR3 2743/4885TSHR 4771/4885HSD17B10 1234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.