Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | MGLL | Q99685 | 1/20 | 0.60 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | GLS | O94925 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21466938 | 0.86 | MAPK1 (0.68) | KMT2ALMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL22246550 | 0.86 | TDP1 (0.63) | KMT2AMGLLLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL4534430 | 0.83 | MGLL (0.64) | KMT2AMGLLNTSR1LMNAALDH1A1 | |
| SCHEMBL7876613 | 0.82 | KMT2A (0.65) | KMT2AMGLLNTSR1LMNAKDM4E | |
| SCHEMBL2593474 | 0.82 | KMT2A (0.65) | KMT2AMGLLNTSR1LMNAHSD17B10 | |
| SCHEMBL3038469 | 0.81 | MAPT (0.56) | KMT2ALMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6138108 | 0.81 | KMT2A (0.69) | KMT2ANTSR1LMNAALDH1A1KDM4E | |
| SCHEMBL29420405 | 0.81 | KMT2A (1.00) | KMT2ANTSR1LMNAKDM4EMEN1 | |
| SCHEMBL1598786 | 0.81 | KMT2A (1.00) | KMT2ANTSR1LMNAKDM4EMEN1 | |
| SCHEMBL1608213 | 0.80 | HDAC6 (0.52) | KMT2AMGLLLMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099732-A1 | MEDICAMENTS USEFUL AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2010-04-22 | — | — | US | claimed |
| EP-2139855-A1 | MEDICAMENTS USEFUL AS POTASSIUM CHANNEL MODULATORS | NeuroSearch A/S (DK) | 2010-01-06 | — | — | EP | claimed |
| WO-2008113747-A1 | MEDICAMENTS USEFUL AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2008-09-25 | — | — | WO | claimed |
| US-20100099732-A1 | MEDICAMENTS USEFUL AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2010-04-22 | — | — | US | disclosed |
| US-20100099732-A1 | MEDICAMENTS USEFUL AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2010-04-22 | — | — | US | disclosed |
| EP-2139855-A1 | MEDICAMENTS USEFUL AS POTASSIUM CHANNEL MODULATORS | NeuroSearch A/S (DK) | 2010-01-06 | — | — | EP | disclosed |
| EP-2139855-A1 | MEDICAMENTS USEFUL AS POTASSIUM CHANNEL MODULATORS | NeuroSearch A/S (DK) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008113747-A1 | MEDICAMENTS USEFUL AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2008-09-25 | — | — | WO | disclosed |
| WO-2008113747-A1 | MEDICAMENTS USEFUL AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2008-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099732-A1 | MEDICAMENTS USEFUL AS POTASSIUM CHANNEL MODULATORS | KCNN2, KCNN1, KCNN3 | KMT2A 424/4885MGLL 2160/4885NTSR1 2506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.