SCHEMBL330805

SCHEMBL330805

[O]C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.43
CA2 P00918 3/20 0.39
CA1 P00915 2/20 0.36
MMP1 P03956 2/20 0.36
MMP2 P08253 2/20 0.36
MMP9 P14780 2/20 0.36
MMP8 P22894 2/20 0.36
MMP13 P45452 2/20 0.36
F2 P00734 1/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
PRSS3 P35030 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1006161 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL1006074 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL1005294 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL1006397 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL1006453 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL1007393 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL843600 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL910572 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL1007075 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL1006646 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 631 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10750742-B2 Pesticidally active pyrazole derivatives SYNGENTA PARTICIPATIONS AG (CH) 2020-08-25 US claimed
US-20200048238-A1 PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2020-02-13 US claimed
US-20190014783-A1 PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2019-01-17 US claimed
EP-4397405-A1 CARBON DIOXIDE CAPTURING AGENT, METAL-ORGANIC FRAMEWORK, AND COMPOUND ENEOS Corporation (JP) 2024-07-10 EP disclosed
US-12034122-B2 Electrolytic solution for lithium-ion secondary battery and lithium-ion secondary battery MURATA MANUFACTURING CO., LTD. (JP) 2024-07-09 US disclosed
CN-115003751-B Polymer composition, molded body, and optical member 住友化学株式会社 2024-07-09 CN disclosed
CN-112074983-B Electrolyte for lithium ion secondary battery and lithium ion secondary battery 株式会社村田制作所 2024-06-04 CN disclosed
US-11993578-B2 Pyrazole-3-carboxylic acid amide derivative and pest control agent KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-05-28 US disclosed
EP-4371979-A1 FORMAMIDE DERIVATIVE AND AGRICULTURAL OR HORTICULTURAL PLANT DISEASE CONTROL AGENT Kumiai Chemical Industry Co., Ltd. (JP) 2024-05-22 EP disclosed
WO-2024101172-A1 (HETERO)ARYL UREA COMPOUND AND INSECTICIDE 日本曹達株式会社 2024-05-16 WO disclosed
EP-4365180-A1 RARE EARTH COMPLEX Tosoh Corporation (JP) 2024-05-08 EP disclosed
EP-1020442-A1 NOVEL DIAMINO COMPOUNDS, POLYAMIC ACID, POLYIMIDE, LIQUID-CRYSTAL ALIGNMENT FILM MADE FROM FILM OF THE POLYIMIDE, AND LIQUID-CRYSTAL DISPLAY ELEMENT CONTAINING THE ALIGNMENT FILM Chisso Corporation (JP) 2000-07-19 EP disclosed
US-6090909-A Uv-ray-dimerized high molecular compound, liquid crystal aligning film using above high molecular compound and liquid crystal display element using above aligning film CHISSO CORPORATION (JP) 2000-07-18 US disclosed
EP-0997463-A1 NAPHTHYRIDINE DERIVATIVES OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 2000-05-03 EP disclosed
EP-0604657-B1 PHOSPHONIC DIESTER DERIVATIVE OTSUKA PHARMA CO LTD (JP) 2000-01-12 EP disclosed
EP-0844243-A1 Sulfonamide compound and method for its production, metal chelate compound employing the sulfonamide compound, and optical recording medium employing the metal chelate compound MITSUBISHI CHEMICAL CORPORATION (JP) 1998-05-27 EP disclosed
US-5707997-A ANALGESICS OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1998-01-13 US disclosed
EP-0714898-A1 PYRAZOLO [1,5-a]PYRIMIDINE DERIVATIVE OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1996-06-05 EP disclosed
US-5376665-A Antidiabetic agent, hypoglycemic agent OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1994-12-27 US disclosed
EP-0604657-A1 PHOSPHONIC DIESTER DERIVATIVE OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1994-07-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11993578-B2 Pyrazole-3-carboxylic acid amide derivative and pest control agent H1-3, HDAC3, H1-0 LMNA 4131/4885THRB 1472/4885CA2 275/4885
US-20190014783-A1 PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES ACHE, AADAC, CAT LMNA 2586/4885THRB 3083/4885CA2 2063/4885
US-10750742-B2 Pesticidally active pyrazole derivatives ACHE, AADAC, CAT LMNA 2586/4885THRB 3083/4885CA2 2063/4885
US-20200048238-A1 PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES ACHE, AADAC, CAT LMNA 2318/4885THRB 3040/4885CA2 2168/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.