SCHEMBL3308498

SCHEMBL3308498

Cc1c(O)c(O)c(Cl)c(O)c1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
HPGD P15428 3/20 0.44
HSD17B10 Q99714 3/20 0.44
ALDH1A1 P00352 2/20 0.44
MAPT P10636 2/20 0.44
MEN1 O00255 1/20 0.44
LMNA P02545 1/20 0.44
KMT2A Q03164 1/20 0.44
CASP1 P29466 1/20 0.36
CYP3A4 P08684 1/20 0.33
CHRM1 P11229 1/20 0.33
ALOX15 P16050 1/20 0.33
MAOA P21397 1/20 0.33
TBXA2R P21731 1/20 0.33
ADRA1A P35348 1/20 0.33
HTR2B P41595 1/20 0.33
CYP1A2 P05177 2/20 0.31
CYP2C9 P11712 2/20 0.31
CYP2C19 P33261 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3221262 0.90 HPGD (0.39) TSHRHPGDHSD17B10ALDH1A1MAPT
SCHEMBL11060919 0.88 HPGD (0.37) TSHRHPGDHSD17B10ALDH1A1MAPT
SCHEMBL17490271 0.83 HPGD (0.44) TSHRHPGDHSD17B10ALDH1A1MAPT
SCHEMBL5587483 0.83 HPGD (0.44) TSHRHPGDHSD17B10ALDH1A1MAPT
SCHEMBL5586757 0.81 HPGD (0.37) TSHRHPGDHSD17B10ALDH1A1MAPT
SCHEMBL5590229 0.81 TSHR (0.53) TSHRHPGDHSD17B10ALDH1A1MAPT
SCHEMBL11509242 0.80 TSHR (0.50) TSHRHPGDHSD17B10ALDH1A1MAPT
SCHEMBL10577820 0.80 TSHR (0.50) TSHRHPGDHSD17B10ALDH1A1MAPT
SCHEMBL24462646 0.78 HPGD (0.39) TSHRHPGDHSD17B10ALDH1A1MAPT
SCHEMBL10922334 0.78 HPGD (0.47) TSHRHPGDHSD17B10ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100098788-A1 Extracts of Curcuma and Methods of Use Thereof HERBALSCIENCE GROUP, LLC 2010-04-22 US disclosed