Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.37 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.37 |
| ▸ | KCNK4 | Q9NYG8 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17771671 | 0.85 | XIAP (0.41) | NOTUMPOLBHTR2AHTR2CCYP11B2 | |
| SCHEMBL17771713 | 0.82 | PGR (0.42) | — | |
| SCHEMBL14310527 | 0.80 | POLB (0.43) | NOTUMPOLBHTR2AHTR2CHDAC6 | |
| SCHEMBL5536032 | 0.79 | ALDH1A1 (0.43) | POLBLMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL17771719 | 0.79 | PGR (0.50) | HDAC6LMNAKDM4E | |
| SCHEMBL5468863 | 0.78 | MAPT (0.38) | POLBHTR2CLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9917021 | 0.78 | SLC6A2 (0.42) | NOTUMHDAC6HDAC1ALDH1A1KDM4E | |
| SCHEMBL17771804 | 0.78 | SIGMAR1 (0.38) | LMNASMN1; SMN2KCNK2ALDH1A1 | |
| SCHEMBL17771703 | 0.78 | KDM4E (0.45) | LMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL17771785 | 0.77 | NOTUM (0.37) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3974147-A | DIHYDRO-HETEROCYCLIC AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1976-08-10 | — | — | US | claimed |
| US-9346805-B2 | Pyrimidyl cyclopentanes as Akt protein kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2016-05-24 | — | — | US | disclosed |
| US-20130087682-A1 | PHOTOELECTRIC CONVERSION DEVICE, IMAGING DEVICE, AND METHOD FOR DRIVING PHOTOELECTRIC CONVERSION DEVICE | FUJIFILM CORPORATION (JP) | 2013-04-11 | — | — | US | disclosed |
| US-8378101-B2 | Organic semiconductor, photoelectric conversion device, imaging device and novel compounds | FUJIFILM CORPORATION (JP) | 2013-02-19 | — | — | US | disclosed |
| US-8278650-B2 | Organic semiconductor, photoelectric conversion element and image device | FUJIFILM CORPORATION (JP) | 2012-10-02 | — | — | US | disclosed |
| US-20100102303-A1 | ORGANIC SEMICONDUCTOR, PHOTOELECTRIC CONVERSION DEVICE, IMAGING DEVICE AND NOVEL COMPOUNDS | FUJIFILM CORPORATION (JP) | 2010-04-29 | — | — | US | disclosed |
| US-20090283758-A1 | ORGANIC SEMICONDUCTOR, PHOTOELECTRIC CONVERSION ELEMENT AND IMAGE DEVICE | FUJIFILM CORPORATION (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100102303-A1 | ORGANIC SEMICONDUCTOR, PHOTOELECTRIC CONVERSION DEVICE, IMAGING DEVICE AND NOVEL COMPOUNDS | H1-3, H1-4, OR10J3 | NOTUM 3557/4885POLB 457/4885HTR2A 4094/4885 |
| US-20090283758-A1 | ORGANIC SEMICONDUCTOR, PHOTOELECTRIC CONVERSION ELEMENT AND IMAGE DEVICE | H1-0, CCNE1, H1-4 | NOTUM 3409/4885POLB 1054/4885HTR2A 4140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.