Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.42 |
| ▸ | SCN1A | P35498 | 4/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 4/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11135724 | 0.94 | TSHR (0.57) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL28499275 | 0.94 | TSHR (0.75) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL28273630 | 0.91 | THRB (0.55) | TSHRTHRBALDH1A1POLBCYP2D6 | |
| SCHEMBL14874 | 0.91 | THRB (0.55) | TSHRTHRBALDH1A1POLBCYP2D6 | |
| SCHEMBL6393908 | 0.90 | TSHR (0.59) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL4635102 | 0.90 | TSHR (0.65) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL28655092 | 0.90 | TSHR (0.59) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL9800939 | 0.90 | THRB (0.53) | TSHRTHRBALDH1A1POLBCYP2D6 | |
| SCHEMBL22684899 | 0.90 | THRB (0.53) | TSHRTHRBALDH1A1POLBCYP2D6 | |
| Hydrochloric Acid SCHEMBL2847352 | 0.90 | THRB (0.53) | TSHRTHRBALDH1A1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113984-A1 | Geometrically shaped hydrogel standoffs for coupling high intensity focused ultrasound | LEONETTI JOSEPH A | 2010-05-06 | — | — | US | disclosed |
| US-20060058705-A1 | Geometrically shaped hydrogel standoffs for coupling high intensity focused ultrasound | UST INC. | 2006-03-16 | — | — | US | disclosed |
| EP-0241160-B1 | Developing method | TOSHIBA KK (JP) | 1994-02-23 | — | — | EP | disclosed |
| US-5236785-A | Surface layer containing copolymer consisting of acrylic monomer having carboxyl group and acrylic monomer having amine and ester groups | TOMOEGAWA PAPER CO., LTD. (JP) | 1993-08-17 | — | — | US | disclosed |
| US-4833059-A | LATENT IMAGES | KABUSHIKI KAISHA TOSHIBA (JP) | 1989-05-23 | — | — | US | disclosed |
| EP-0232442-B1 | IMPROVED BLOOD-PURIFYING MEMBRANE AND PROCESS FOR PREPARATION THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1989-04-26 | — | — | EP | disclosed |
| US-4787977-A | REGENERATED CELLULOSE WITH AMINO CONTAINING POLYMERIC COATING | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1988-11-29 | — | — | US | disclosed |
| EP-0232442-A1 | Improved blood-purifying membrane and process for preparation thereof | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1987-08-19 | — | — | EP | disclosed |