SCHEMBL3310136

SCHEMBL3310136

Nc1cccc(P(=O)(c2cccc(N)c2)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
MAPK1 P28482 1/20 0.52
PTGS1 P23219 5/20 0.46
PGK1 P00558 2/20 0.39
PGK2 P07205 2/20 0.39
P2RX1 P51575 3/20 0.37
KIF11 P52732 1/20 0.36
CYP3A4 P08684 1/20 0.35
CASP1 P29466 1/20 0.35
RECQL P46063 1/20 0.35
GLA P06280 1/20 0.35
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
ACP3 P15309 1/20 0.35
HTR1A P08908 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30645311 1.00 TSHR (0.52) TSHRMAPK1PTGS1PGK1PGK2
SCHEMBL19472449 0.90 MAPK1 (0.45) TSHRMAPK1PTGS1PGK1PGK2
SCHEMBL29617169 0.87 PTGS1 (0.52) TSHRMAPK1PTGS1PGK1PGK2
SCHEMBL7152607 0.87 PTGS1 (0.52) TSHRMAPK1PTGS1PGK1PGK2
SCHEMBL9688354 0.82 CYP3A4 (0.52) TSHRMAPK1CYP3A4CASP1RECQL
SCHEMBL30471399 0.82 CYP3A4 (0.52) TSHRMAPK1CYP3A4CASP1RECQL
SCHEMBL19477881 0.81 KIF11 (0.48) TSHRMAPK1PTGS1P2RX1KIF11
SCHEMBL7616716 0.80 P2RX1 (0.46) TSHRPGK1PGK2P2RX1KIF11
SCHEMBL1536240 0.76 MAOA (0.52) TSHRCYP3A4CASP1RECQLGAA
SCHEMBL21636282 0.76 MAOA (0.52) TSHRCYP3A4CASP1RECQLGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118725244-A Polyurethane elastomer with fluorine-containing polyimide oligomer chain extension and preparation method thereof 山东奥卓新材料有限公司 2024-10-01 CN claimed
US-20240150524-A1 POLYIMIDES HAVING LOW DIELECTRIC LOSS SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2024-05-09 US claimed
WO-2022175169-A1 POLYIMIDES HAVING LOW DIELECTRIC LOSS SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2022-08-25 WO claimed
US-20090242823-A1 PROCESS FOR PREPARING POLYIMIDE BASED COMPOSITIONS USEFUL IN HIGH FREQUENCY CIRCUITRY APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY 2009-10-01 US claimed
EP-2001676-A1 CAPACITIVE POLYIMIDE LAMINATE E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-12-17 EP claimed
EP-2001942-A1 PROCESS FOR PREPARING POLYIMIDE BASED COMPOSITIONS USEFUL IN HIGH FREQUENCY CIRCUITRY APPLICATIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-12-17 EP claimed
WO-2007126533-A1 CAPACITIVE POLYIMIDE LAMINATE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-11-08 WO claimed
WO-2007117372-A1 PROCESS FOR PREPARING POLYIMIDE BASED COMPOSITIONS USEFUL IN HIGH FREQUENCY CIRCUITRY APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-10-18 WO claimed
US-20070232734-A1 Polyimide based compositions useful in high frequency circuitry applications and methods relating thereto KANAKARAJAN KARTHIKEYAN 2007-10-04 US claimed
US-20070231588-A1 Capacitive polyimide laminate E. I. DU PONT DE NEMOURS AND COMPANY 2007-10-04 US claimed
EP-1672009-A1 Thermally conductive polyimide film composites having high thermal conductivity useful in an electronic device E.I.Du pont de nemours and company (US) 2006-06-21 EP claimed
US-20060124693-A1 Thermally conductive polyimide film composites having high mechanical elongation useful as a heat conducting portion of an electronic device E. I. DU PONT DE NEMOURS AND COMPANY 2006-06-15 US claimed
US-20060127686-A1 Thermally conductive polyimide film composites having high thermal conductivity useful in an electronic device E. I. DU PONT DE NEMOURS AND COMPANY 2006-06-15 US claimed
CN-118725244-A Polyurethane elastomer with fluorine-containing polyimide oligomer chain extension and preparation method thereof 山东奥卓新材料有限公司 2024-10-01 CN disclosed
US-20240166818-A1 POLYIMIDES HAVING LOW DIELECTRIC LOSS SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2024-05-23 US disclosed
US-20240150524-A1 POLYIMIDES HAVING LOW DIELECTRIC LOSS SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2024-05-09 US disclosed
EP-1672009-A1 Thermally conductive polyimide film composites having high thermal conductivity useful in an electronic device E.I.Du pont de nemours and company (US) 2006-06-21 EP disclosed
EP-1672008-A1 Thermally conductive polyimide film composites having high mechanical elongation useful as a heat conducting portion of an electronic device E.I.Du pont de nemours and company (US) 2006-06-21 EP disclosed
US-20060124693-A1 Thermally conductive polyimide film composites having high mechanical elongation useful as a heat conducting portion of an electronic device E. I. DU PONT DE NEMOURS AND COMPANY 2006-06-15 US disclosed
US-20060127686-A1 Thermally conductive polyimide film composites having high thermal conductivity useful in an electronic device E. I. DU PONT DE NEMOURS AND COMPANY 2006-06-15 US disclosed