SCHEMBL7616716

SCHEMBL7616716

O=P(c1ccccc1)(c1ccccc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
P2RX1 P51575 2/20 0.46
PGK1 P00558 2/20 0.44
PGK2 P07205 2/20 0.44
ALDH1A1 P00352 1/20 0.44
TSHR P16473 1/20 0.44
KIF11 P52732 1/20 0.43
RXRA P19793 2/20 0.42
RXRB P28702 2/20 0.42
RXRG P48443 2/20 0.42
PTPN1 P18031 2/20 0.41
PTPN5 P54829 2/20 0.41
TACR1 P25103 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
ACP3 P15309 2/20 0.40
P2RX4 Q99571 1/20 0.39
P2RX7 Q99572 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19472451 0.88 PGK1 (0.43) P2RX1PGK1PGK2ALDH1A1TSHR
SCHEMBL8164654 0.86 PGK1 (0.51) PGK1PGK2ALDH1A1TSHRKIF11
SCHEMBL7154044 0.83 KIF11 (0.58) P2RX1PGK1PGK2ALDH1A1TSHR
SCHEMBL19477881 0.81 KIF11 (0.48) P2RX1TSHRKIF11RXRARXRB
SCHEMBL11991776 0.80 P2RX1 (0.37) P2RX1PGK1PGK2ALDH1A1TSHR
SCHEMBL3310136 0.80 TSHR (0.52) P2RX1PGK1PGK2TSHRKIF11
SCHEMBL30645311 0.80 TSHR (0.52) P2RX1PGK1PGK2TSHRKIF11
SCHEMBL5827130 0.78 ALDH1A1 (0.41) P2RX1PGK1PGK2ALDH1A1TSHR
SCHEMBL11991045 0.78 MEN1 (0.38) P2RX1PGK1PGK2TSHRKIF11
SCHEMBL5450490 0.78 CA2 (0.50) ALDH1A1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10240090-B2 Fire retardant materials and devices including same THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) 2019-03-26 US disclosed
US-10240090-B2 Fire retardant materials and devices including same THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) 2019-03-26 US disclosed
CN-109216770-A A kind of nonaqueous lithium ion battery electrolyte and the lithium ion battery using the electrolyte 珠海光宇电池有限公司 2019-01-15 CN disclosed
EP-3186308-B1 FIRE RETARDANT MATERIALS AND DEVICES INCLUDING SAME THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIV OF NEVADA LAS VE (US) 2018-12-26 EP disclosed
US-20170298278-A1 FIRE RETARDANT MATERIALS AND DEVICES INCLUDING SAME KISHOLOYGOSWAMI LLC 2017-10-19 US disclosed
US-20170298278-A1 FIRE RETARDANT MATERIALS AND DEVICES INCLUDING SAME KISHOLOYGOSWAMI LLC 2017-10-19 US disclosed
EP-3186308-A1 FIRE RETARDANT MATERIALS AND DEVICES INCLUDING SAME The Board Of Regents Of The Nevada System Of Higher Education on behalf of the Univeristy Of Nevada-Las Vegas (US) 2017-07-05 EP disclosed
WO-2016033520-A1 FIRE RETARDANT MATERIALS AND DEVICES INCLUDING SAME THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) 2016-03-03 WO disclosed
US-6342638-B1 Triarylphosphine oxide derivatives containing fluorine substituents KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2002-01-29 US disclosed