Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3310364 | 0.87 | ALDH1A1 (0.48) | ALDH1A1HTTPOLBKMT2AHRH3 | |
| SCHEMBL3301884 | 0.85 | GPR119 (0.51) | GPR119ALDH1A1CHEK2POLBKMT2A | |
| SCHEMBL3310315 | 0.83 | HRH3 (0.61) | ALDH1A1HTTKMT2AHRH3 | |
| SCHEMBL3310263 | 0.83 | KMT2A (0.55) | ALDH1A1HTTPOLBKMT2AHRH3 | |
| SCHEMBL3310576 | 0.83 | HRH3 (0.47) | ALDH1A1HTTPOLBKMT2AHRH3 | |
| SCHEMBL3308511 | 0.82 | MEN1 (0.55) | ALDH1A1HTTKMT2AHRH3 | |
| SCHEMBL3309315 | 0.82 | MEN1 (0.58) | ALDH1A1HTTKMT2AHRH3 | |
| SCHEMBL3313879 | 0.82 | ALDH1A1 (0.48) | ALDH1A1HTTPOLBKMT2AHRH3 | |
| SCHEMBL3311278 | 0.81 | KMT2A (0.57) | ALDH1A1HTTKMT2AHRH3 | |
| SCHEMBL3310391 | 0.81 | KMT2A (0.60) | ALDH1A1HTTKMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113776-A1 | PYRAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO.,LTD. (JP) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113776-A1 | PYRAZOLE DERIVATIVE | HRH3, HRH4, HRH1 | GPR119 7/4885ALDH1A1 2729/4885HTT 125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.