Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP1A1 | P05023 | 1/20 | 0.43 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.43 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.43 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.43 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.43 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.43 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.43 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.43 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | USP2 | O75604 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 6/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6756618 | 0.80 | ATP1A1 (0.40) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL6760162 | 0.77 | USP2 (0.45) | MAPTUSP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6754289 | 0.75 | MAPT (0.48) | MAPTUSP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL22549150 | 0.75 | NR2E1 (0.47) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL3312215 | 0.75 | IDO1 (0.41) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL31729790 | 0.73 | NR2E1 (0.44) | NR2E1POLBGAAIKBKBMAPK1 | |
| SCHEMBL6754326 | 0.72 | MAP4K4 (0.49) | MAPTUSP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13225982 | 0.72 | SMN1; SMN2 (0.49) | NR2E1CYP3A4POLBIKBKBMAPK1 | |
| SCHEMBL716180 | 0.71 | TSHR (0.50) | NR2E1MAPTPOLBGAAIKBKB | |
| SCHEMBL29576147 | 0.71 | TSHR (0.50) | NR2E1MAPTPOLBGAAIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8217045-B2 | Organic compounds | NOVARTIS AG (CH) | 2012-07-10 | — | — | US | disclosed |
| US-20100113467-A1 | Organic Compounds | NOVARTIS AG | 2010-05-06 | — | — | US | disclosed |
| CN-101687801-A | Ethers of naphtalene carboxylic acid amides as cancer cure | NOVARTIS AG | 2010-03-31 | — | — | CN | disclosed |
| EP-2146964-A2 | ETHERS OF NAPHTALENE CARBOXYLIC ACID AMIDES AS CANCER CURE | Novartis Ag (CH) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008125691-A2 | ETHERS OF NAPHTALENE CARBOXYLIC ACID AMIDES AS CANCER CURE | NOVARTIS AG (CH) | 2008-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113467-A1 | Organic Compounds | SLCO2A1, SLCO1B1, SLCO2B1 | ATP1A1 568/4885ATP1B1 766/4885ATP1A3 1791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.