Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TTK | P33981 | 3/20 | 0.36 |
| ▸ | KAT5 | Q92993 | 3/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | WNT1 | P04628 | 1/20 | 0.33 |
| ▸ | KAT7 | O95251 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6756618 | 0.81 | ATP1A1 (0.40) | USP2TP53MAPK1MAPTDYRK1A | |
| SCHEMBL6754289 | 0.78 | MAPT (0.48) | USP2TP53MAPTDYRK1AGSK3B | |
| SCHEMBL3311968 | 0.77 | ATP1A1 (0.43) | USP2TP53MAPK1MAPTDYRK1A | |
| SCHEMBL4756995 | 0.76 | DYRK1A (0.47) | MAPTDYRK1AGSK3BMAP4K4SMN1; SMN2 | |
| SCHEMBL6754326 | 0.75 | MAP4K4 (0.49) | USP2MAPTDYRK1ACYP3A4PRMT5 | |
| SCHEMBL6755660 | 0.75 | DYRK1A (0.38) | MAPK1MAPTDYRK1AGSK3BKAT5 | |
| SCHEMBL4756960 | 0.75 | DYRK1A (0.48) | MAPK1DYRK1AGSK3BMAP4K4KAT5 | |
| SCHEMBL14077000 | 0.74 | USP2 (0.66) | USP2TP53MAPK1MAPTDYRK1A | |
| SCHEMBL12492258 | 0.74 | TP53 (0.51) | USP2TP53MAPK1MAPTDYRK1A | |
| SCHEMBL12491967 | 0.73 | MAPT (0.49) | USP2TP53MAPK1MAPTDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040087798-A1 | Novel amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-06 | — | — | US | disclosed |
| US-20030176454-A1 | N-coating heterocyclic compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-09-18 | — | — | US | disclosed |
| EP-1264820-A1 | NOVEL AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176454-A1 | N-coating heterocyclic compounds | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, GNE, NIT2 | USP2 3081/4885TP53 4553/4885MAPK1 2263/4885 |
| US-20040087798-A1 | Novel amide compounds | H1-2, H1-0, H1-3 | USP2 4276/4885TP53 2814/4885MAPK1 234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.