SCHEMBL3314775

SCHEMBL3314775

NC1CCCN(C(=O)c2ccccc2)C1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.59
ALDH1A1 P00352 4/20 0.53
ACHE P22303 1/20 0.53
USP2 O75604 1/20 0.53
L3MBTL3 Q96JM7 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
KDM4E B2RXH2 2/20 0.52
POLB P06746 1/20 0.52
LMNA P02545 1/20 0.52
HIF1A Q16665 1/20 0.52
HSD11B1 P28845 1/20 0.52
PADI4 Q9UM07 1/20 0.51
MAPK1 P28482 1/20 0.50
GLA P06280 1/20 0.50
HSD17B10 Q99714 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
ATM Q13315 1/20 0.50
RECQL P46063 1/20 0.50
PDE2A O00408 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3314769 1.00 HPGD (0.59) HPGDALDH1A1ACHEUSP2L3MBTL3
SCHEMBL27970474 1.00 HPGD (0.59) HPGDALDH1A1ACHEUSP2L3MBTL3
Hydrochloric Acid SCHEMBL30708065 0.98 HPGD (0.57) HPGDALDH1A1ACHEUSP2L3MBTL3
SCHEMBL4706190 0.95 HPGD (0.62) HPGDALDH1A1ACHEUSP2L3MBTL3
SCHEMBL2130912 0.90 ACHE (0.60) HPGDACHEL3MBTL3L3MBTL1KDM4E
Hydrochloric Acid SCHEMBL7937517 0.89 ACHE (0.58) HPGDACHEL3MBTL3L3MBTL1KDM4E
Hydrochloric Acid SCHEMBL7937513 0.89 ACHE (0.58) HPGDACHEL3MBTL3L3MBTL1KDM4E
SCHEMBL14218322 0.87 HPGD (0.64) HPGDALDH1A1ACHEUSP2L3MBTL3
SCHEMBL3314252 0.84 GLA (0.70) HPGDALDH1A1L3MBTL1POLBHSD11B1
SCHEMBL3314246 0.84 GLA (0.70) HPGDALDH1A1L3MBTL1POLBHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104034814-B The HPLC analytical approach of 3-amino piperidine HEBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2016-02-24 CN claimed
CN-104034814-A HPLC (High Performance Liquid Chromatography) analysis method for 3-aminopiperidine UNIV HEBEI SCIENCE & TECH 2014-09-10 CN claimed
EP-4452414-A2 IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF GILEAD SCIENCES, INC. (US) 2024-10-30 EP disclosed
US-20240124412-A1 IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF GILEAD SCIENCES, INC. 2024-04-18 US disclosed
CN-113135918-B Pyrazolo [1,2] diaza compounds 鲁南制药集团股份有限公司 2023-08-11 CN disclosed
WO-2023122581-A2 IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF GILEAD SCIENCES, INC. (US) 2023-06-29 WO disclosed
US-20230121337-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS, INC. 2023-04-20 US disclosed
WO-2022272106-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS, INC. (US) 2022-12-29 WO disclosed
EP-2123769-B1 METHOD FOR PRODUCING OPTICALLY ACTIVE 3-AMINOPIPERIDINE OR SALT THEREOF KANEKA CORP (JP) 2016-05-18 EP disclosed
CN-104034814-B The HPLC analytical approach of 3-amino piperidine HEBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2016-02-24 CN disclosed
CN-104034814-B The HPLC analytical approach of 3-amino piperidine HEBEI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2016-02-24 CN disclosed
CN-104034814-A HPLC (High Performance Liquid Chromatography) analysis method for 3-aminopiperidine UNIV HEBEI SCIENCE & TECH 2014-09-10 CN disclosed
CN-104034814-A HPLC (High Performance Liquid Chromatography) analysis method for 3-aminopiperidine UNIV HEBEI SCIENCE & TECH 2014-09-10 CN disclosed
US-20130079525-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE 3-AMINOPIPERIDINE OR SALT THEREOF KANEKA CORPORATION (JP) 2013-03-28 US disclosed
US-8338142-B2 Method for producing optically active 3-aminopiperidine or salt thereof KANEKA CORPORATION (JP) 2012-12-25 US disclosed
US-20100105917-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE 3-AMINOPIPERIDINE OR SALT THEREOF KANEKA CORPORATION (JP) 2010-04-29 US disclosed
EP-2123769-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE 3-AMINOPIPERIDINE OR SALT THEREOF Kaneka Corporation (JP) 2009-11-25 EP disclosed
US-7332509-B2 Heterocyclic amides, a process for their preparation, compositions comprising them and their use MERIAL LIMITED (US) 2008-02-19 US disclosed
EP-0275759-B1 SUBSTITUTED 3-PIPERIDINE AMINES OR 3-AZEPIN AMINES, THEIR PREPARATION AND THERAPEUTIC USES RIOM LABORATOIRES- C.E.R.M. "R.L.-CERM" - (S.A.) (FR) 1992-01-29 EP disclosed
EP-0275759-A1 Substituted 3-piperidine amines or 3-azepin amines, their preparation and therapeutic uses RIOM LABORATOIRES- C.E.R.M. "R.L.-CERM" - (S.A.) (FR) 1988-07-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230121337-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CDK2, CDK20, CDK2AP2 HPGD 1161/4885ALDH1A1 3716/4885ACHE 3485/4885
US-20130079525-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE 3-AMINOPIPERIDINE OR SALT THEREOF NPEPPS, APEH, DNPEP HPGD 479/4885ALDH1A1 1293/4885ACHE 356/4885
US-20240124412-A1 IKAROS ZINC FINGER FAMILY DEGRADERS AND USES THEREOF IKZF2, IKZF1, IKZF3 HPGD 3659/4885ALDH1A1 3576/4885ACHE 3804/4885
US-20100105917-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE 3-AMINOPIPERIDINE OR SALT THEREOF NPEPPS, APEH, DNPEP HPGD 479/4885ALDH1A1 1293/4885ACHE 356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.