Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5097175 | 0.85 | OPRM1 (0.48) | MEN1KMT2AOPRM1CYP3A4CYP2C9 | |
| SCHEMBL9282167 | 0.81 | GAA (0.51) | MEN1KMT2AOPRM1CYP3A4ALDH1A1 | |
| SCHEMBL6794727 | 0.81 | GRM7 (0.51) | MEN1KMT2AOPRM1CYP3A4CYP2C9 | |
| SCHEMBL3313904 | 0.79 | OPRM1 (0.42) | MEN1KMT2AOPRM1BCAT2CYP3A4 | |
| Hydrochloric Acid SCHEMBL28984872 | 0.74 | SOS1 (0.42) | SLC6A4SLC6A3MAPK1ALDH1A1HTT | |
| SCHEMBL6023381 | 0.73 | SLC6A4 (0.44) | MEN1KMT2ASLC6A4SLC6A3CYP3A4 | |
| SCHEMBL31023924 | 0.71 | CTSD (0.50) | KMT2ABCAT2CYP3A4CYP2C9PDGFRA | |
| SCHEMBL10211041 | 0.71 | EPHX1 (0.46) | BCAT2CYP3A4CYP2C9PDGFRAMAPK1 | |
| SCHEMBL13447469 | 0.71 | HDAC3 (0.47) | BCAT2CYP3A4CYP2C9PDGFRAMAPK1 | |
| SCHEMBL13711161 | 0.71 | EPHX1 (0.46) | BCAT2CYP3A4CYP2C9PDGFRAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105651-A1 | ANTAGONISTS OF SNS SODIUM CHANNELS | VERNALIS (R&D) LIMITED (GB) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105651-A1 | ANTAGONISTS OF SNS SODIUM CHANNELS | CNR1, OPRL1, CHRNA10 | MEN1 2995/4885KMT2A 3099/4885OPRM1 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.