Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.40 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH4 | P08319 | 1/20 | 0.38 |
| ▸ | ADH7 | P40394 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17772681 | 1.00 | ACE2 (0.45) | ACE2OPRM1SPHK1ZDHHC7LMNA | |
| SCHEMBL3314131 | 1.00 | ACE2 (0.45) | ACE2OPRM1SPHK1ZDHHC7LMNA | |
| SCHEMBL8107298 | 0.98 | OPRM1 (0.44) | ACE2OPRM1SPHK1ZDHHC7LMNA | |
| SCHEMBL3315690 | 0.98 | OPRM1 (0.44) | ACE2OPRM1SPHK1ZDHHC7LMNA | |
| SCHEMBL28320909 | 0.91 | OPRM1 (0.39) | ACE2OPRM1SPHK1ZDHHC7SMPD1 | |
| SCHEMBL12112393 | 0.90 | — | — | |
| SCHEMBL13701664 | 0.90 | — | — | |
| SCHEMBL14525660 | 0.84 | ACE2 (0.48) | ACE2OPRM1SPHK1ZDHHC7LMNA | |
| SCHEMBL28735633 | 0.84 | ACE2 (0.48) | ACE2OPRM1SPHK1ZDHHC7LMNA | |
| SCHEMBL28735666 | 0.84 | ACE2 (0.48) | ACE2OPRM1SPHK1ZDHHC7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669243-B2 | Delivery of hydrophobic benefit agents from bodywashes and the like onto a keratinous substrate | BASF SE (DE) | 2017-06-06 | — | — | US | disclosed |
| EP-2132167-B1 | METHOD FOR THE PRODUCTION OF beta-KETONITRILES | BASF SE (DE) | 2013-12-25 | — | — | EP | disclosed |
| US-8501748-B2 | Method for the production of β-ketonitriles | BASF SE (DE) | 2013-08-06 | — | — | US | disclosed |
| US-20130005970-A1 | Method for the production of beta-ketonitriles | BASF SE (DE) | 2013-01-03 | — | — | US | disclosed |
| US-8309751-B2 | Method for the production of β-ketonitriles | BASF SE (DE) | 2012-11-13 | — | — | US | disclosed |
| US-8263972-B2 | Organic electroluminescent device and display medium | FUJI XEROX CO. LTD. (JP) | 2012-09-11 | — | — | US | disclosed |
| US-8263972-B2 | Organic electroluminescent device and display medium | FUJI XEROX CO. LTD. (JP) | 2012-09-11 | — | — | US | disclosed |
| US-8217391-B2 | Organic semiconductor transistor, method of producing the same, and electronic device | FUJI XEROX CO., LTD. (JP) | 2012-07-10 | — | — | US | disclosed |
| US-8217391-B2 | Organic semiconductor transistor, method of producing the same, and electronic device | FUJI XEROX CO., LTD. (JP) | 2012-07-10 | — | — | US | disclosed |
| EP-2233488-B1 | THIAZOLOTHIAZOLE DERIVATIVES AND ORGANIC ELECTRONIC DEVICE USING THE SAME | FUJI XEROX CO LTD (JP) | 2011-01-12 | — | — | EP | disclosed |
| US-20100105903-A1 | Method for the production of beta-ketonitriles | BASF SE (DE) | 2010-04-29 | — | — | US | disclosed |
| EP-2132167-A1 | METHOD FOR THE PRODUCTION OF -KETONITRILES | BASF SE (DE) | 2009-12-16 | — | — | EP | disclosed |
| WO-2009064975-A1 | QUINOXALINE-CONTAINING COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2009-05-22 | — | — | WO | disclosed |
| US-20080247975-A1 | Sunscreen and personal care compositions comprising a select copolymer | CIBA CORP. | 2008-10-09 | — | — | US | disclosed |
| WO-2008107397-A1 | METHOD FOR THE PRODUCTION OF β-KETONITRILES | BASF SE (DE) | 2008-09-12 | — | — | WO | disclosed |
| US-20080019929-A1 | Micro-Particulate Organic Uv Absorber Composition | CIBA SPECIALTY CHEMICALS CORP. | 2008-01-24 | — | — | US | disclosed |
| US-7198827-B1 | Nematic liquid crystal composition and liquid crystal display device using the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2007-04-03 | — | — | US | disclosed |
| US-6344307-B1 | RESIN HAVING AT LEAST ONE APROTIC AMMONIUM, PHOSPHONIUM OR SULFONIUM SALT; COMPOUND HAVING TWO OR MORE VINYLETHER GROUPS IN A MOLECULE; AND COMPOUND WHICH GENERATES AN ACID UPON IRRADIATION WITH ACTINIC ENERGY RAYS | KANSAI PAINT CO., LTD. (JP) | 2002-02-05 | — | — | US | disclosed |
| US-5536881-A | Lubricating oil for compression-type refrigerators and polyoxyalkylene glycol derivatives | IDEMITSU KOSAN CO., LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5269955-A | 1,1,1,2-tetrafluoroethylene refrigerant | IDEMITSU KOSAN CO., LTD. (JP) | 1993-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130005970-A1 | Method for the production of beta-ketonitriles | AKR1C3, AKR1C4, AKR1C1 | ACE2 1552/4885OPRM1 3316/4885SPHK1 195/4885 |
| US-20080247975-A1 | Sunscreen and personal care compositions comprising a select copolymer | MSH6, CUTA, ERCC5 | ACE2 4062/4885OPRM1 4712/4885SPHK1 3944/4885 |
| US-20100105903-A1 | Method for the production of beta-ketonitriles | AKR1C3, AKR1C4, AKR1C1 | ACE2 1552/4885OPRM1 3316/4885SPHK1 195/4885 |
| US-20080019929-A1 | Micro-Particulate Organic Uv Absorber Composition | PCNA, FASN, CCNO | ACE2 3132/4885OPRM1 516/4885SPHK1 744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.