SCHEMBL3315840

SCHEMBL3315840

C=C(C)COc1cccc(C(=O)O)c1

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.62
NR4A2 P43354 9/20 0.58
PLA2G4B P0C869 2/20 0.57
AKR1C3 P42330 1/20 0.53
NR4A1 P22736 2/20 0.52
NR4A3 Q92570 2/20 0.52
MAOB P27338 1/20 0.51
MRGPRX4 Q96LA9 1/20 0.51
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
NR1H4 Q96RI1 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30361079 1.00 KMT2A (0.62) KMT2ANR4A2PLA2G4BAKR1C3NR4A1
SCHEMBL1092175 0.89 MAOB (0.60) KMT2AMAOB
SCHEMBL12411431 0.87 KMT2A (0.66) KMT2ANR4A2PLA2G4BAKR1C3NR4A1
SCHEMBL203154 0.86 PARP1 (0.58) KMT2AMAOB
SCHEMBL21546006 0.86 MAOB (0.47) KMT2APLA2G4BMAOB
SCHEMBL4234393 0.84 SMN1; SMN2 (0.57) KMT2AMRGPRX4NPC1RAB9A
SCHEMBL10167730 0.83 NR4A2 (0.65) KMT2ANR4A2PLA2G4BAKR1C3NR4A1
SCHEMBL17044563 0.83 PLA2G2A (0.53) KMT2APLA2G4B
SCHEMBL9622079 0.82 LMNA (0.52) KMT2ANPC1RAB9A
SCHEMBL3962055 0.81 PLA2G4B (0.68) KMT2ANR4A2PLA2G4BAKR1C3NR4A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115872661-B Viscosity-reducing polycarboxylate superplasticizer and preparation method thereof 科之杰新材料集团有限公司 2024-02-20 CN claimed
CN-115872661-A Viscosity-reducing polycarboxylate superplasticizer and preparation method thereof 科之杰新材料集团有限公司 2023-03-31 CN claimed
EP-0334778-B1 AROMATIC POLYAMIDE-IMIDES FUNCTIONALISED WITH ALKENYLOXY GROUPS, A METHOD FOR THEIR PREPARATION AND THEIR USE TO PREPARE CROSSLINKED POLYMERS CIBA-GEIGY AG (CH) 1992-04-15 EP claimed
US-4927899-A Alkenyloxylated aromatic polyamidoimides RHONE-POULENC CHIMIE (FR) 1990-05-22 US claimed
US-20250043047-A1 POLYMERIZABLE MONOMERS AND METHOD OF POLYMERIZING THE SAME ALIGN TECHNOLOGY INC (US) 2025-02-06 US disclosed
US-12152092-B2 Polymerizable monomers and method of polymerizing the same ALIGN TECHNOLOGY, INC. (US) 2024-11-26 US disclosed
CN-115872661-B Viscosity-reducing polycarboxylate superplasticizer and preparation method thereof 科之杰新材料集团有限公司 2024-02-20 CN disclosed
CN-115872661-A Viscosity-reducing polycarboxylate superplasticizer and preparation method thereof 科之杰新材料集团有限公司 2023-03-31 CN disclosed
US-20210002396-A1 POLYMERIZABLE MONOMERS AND METHOD OF POLYMERIZING THE SAME ALIGN TECHNOLOGY, INC. 2021-01-07 US disclosed
US-10781274-B2 Polymerizable monomers and method of polymerizing the same ALIGN TECHNOLOGY, INC. (US) 2020-09-22 US disclosed
US-10781275-B2 Polymerizable monomers and method of polymerizing the same ALIGN TECHNOLOGY, INC. (US) 2020-09-22 US disclosed
US-20200040113-A1 POLYMERIZABLE MONOMERS AND METHOD OF POLYMERIZING THE SAME ALIGN TECHNOLOGY, INC. 2020-02-06 US disclosed
EP-0595995-B1 ARYLAMIDOALKYL- AND ARYLAMINOALKYL-N-HYDROXYUREA COMPOUNDS AND -N-HYDROXYFORMAMIDE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY ABBOTT LAB (US) 1997-01-15 EP disclosed
US-5514702-A Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity ABBOTT LABORATORIES (US) 1996-05-07 US disclosed
US-5470920-A Impregnating solutions based on at least one reactive thermoplastic poly (imide-amide) oligomer and a coreactant, which can be used especially for the production of preimpregnated intermediate articles CIBA-GEIGY CORPORATION (US) 1995-11-28 US disclosed
EP-0595995-A4 ARYLAMIDOALKYL-N-HYDROXYUREA COMPOUNDS HAVING LIPOXYGENASE INHIBITORY ACTIVITY ABBOTT LAB (US) 1994-08-24 EP disclosed
EP-0595995-A1 ARYLAMIDOALKYL-N-HYDROXYUREA COMPOUNDS HAVING LIPOXYGENASE INHIBITORY ACTIVITY. ABBOTT LAB (US) 1994-05-11 EP disclosed
US-5214204-A Inhibitors of biosynthesis of leukotrienes ABBOTT LABORATORIES (US) 1993-05-25 US disclosed
WO-1993002037-A1 ARYLAMIDOALKYL-N-HYDROXYUREA COMPOUNDS HAVING LIPOXYGENASE INHIBITORY ACTIVITY ABBOTT LABORATORIES (US) 1993-02-04 WO disclosed
US-4927899-A Alkenyloxylated aromatic polyamidoimides RHONE-POULENC CHIMIE (FR) 1990-05-22 US disclosed