SCHEMBL3315855

SCHEMBL3315855

[NH]C(=O)[C@@H](N)Cc1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.70
ALPI P09923 1/20 0.70
PKM P14618 1/20 0.70
PTGS1 P23219 1/20 0.70
XIAP P98170 1/20 0.70
SLC15A1 P46059 1/20 0.59
LTA4H P09960 1/20 0.56
SLC1A3 P43003 2/20 0.55
SLC1A2 P43004 2/20 0.55
SLC1A1 P43005 2/20 0.55
HDAC8 Q9BY41 2/20 0.53
EPHX1 P07099 2/20 0.52
CYP1A2 P05177 1/20 0.52
LAP3 P28838 3/20 0.50
ANPEP P15144 1/20 0.50
CTSC P53634 1/20 0.50
SRR Q9GZT4 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3208566 1.00 SLC7A5 (0.70) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL7722345 1.00 SLC7A5 (0.70) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL9266010 0.83 SLC7A5 (0.70) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL34465319 0.83 SLC7A5 (0.92) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL23159186 0.83 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL16398196 0.83 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL8119 0.83 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL385804 0.83 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL8118 0.83 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL16398197 0.83 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230219973-A1 DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF MOLECURE S.A. (PL) 2023-07-13 US claimed
WO-2023119233-A1 DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF MOLECURE S.A. (PL) 2023-06-29 WO claimed
US-8287835-B2 Organically functionalized carbon nanocapsule INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2012-10-16 US claimed
US-20080160308-A1 Organically functionalized carbon nanocapsule INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2008-07-03 US claimed
EP-1132380-B1 E-Isomeric fullerene derivatives CHIANG LONG Y (TW) 2008-01-23 EP claimed
US-7132572-B2 Fullerene compounds Chiang, Long Y. (US) 2006-11-07 US claimed
US-6949660-B2 Chiral (1pyrrolino) fullerene derivatives SETH NANOTECHNOLOGY, INCORPORATED (US) 2005-09-27 US claimed
US-20050191229-A1 Fullerene compounds CHIANG, LONG Y. 2005-09-01 US claimed
US-6790963-B2 STEREOSPECIFIC PHOTODYANMIC THERAPY SENSITIZERS TO ENHANCE CYTOTOXICITY OF ANTITUMOR AGENTS; FULLEROPYRROLIDINE COMPOUNDS CHIANG, LONG Y. (TW) 2004-09-14 US claimed
US-6767906-B2 INHIBIT P34CDC2/CYCLIN BCDC13 KINASE AND PROTEIN TYROSINE KINASE PP60C-SRC AND CAN BE USED FOR TREATMENT OF HYPERPROLIFERATIVE DISEASES, FOR EXAMPLE CHEMOTHERAPY OF TUMOURS OR OSTEOPOROSIS. NOVARTIS AG (CH) 2004-07-27 US claimed
US-6046361-A Polyorganofullerenes SETHNANOTECHNOLOGY, INCORPORATED 2000-04-04 US claimed
US-6020523-A Polyorganofullerenes SETHNANOTECHNOLOGY, INCORPORATED 2000-02-01 US claimed
EP-0919520-A2 Fullernes substituted by several organic groups Chiang, Long Y. (TW) 1999-06-02 EP claimed
CN-1202896-A Purine derivatives and processes for their preparation 诺瓦提斯公司 1998-12-23 CN claimed
EP-0874846-A1 PURINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION Novartis AG (CH) 1998-11-04 EP claimed
WO-1997016452-A1 PURINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION NOVARTIS AG (CH) 1997-05-09 WO claimed
EP-0236164-B1 DERIVATIVES OF N-ALPHA-ARYLSOLFONYLAMINOACYL P-AMIDINO-PHENYLALANINAMIDES, PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND THEIR INTERMEDIATES SANOFI (FR) 1990-09-12 EP claimed
EP-0236164-A1 Derivatives of N-alpha-arylsolfonylaminoacyl p-amidino-phenylalaninamides, process for their preparation, their use as medicaments and their intermediates SANOFI (FR) 1987-09-09 EP claimed
EP-0071926-B1 NEW RIBOFURANURONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-10-08 EP claimed
EP-0071926-A1 New ribofuranuronic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-02-16 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219973-A1 DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF USP7, USP28, USP1 SLC7A5 3588/4885ALPI 2368/4885PKM 3733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.