SCHEMBL3316840

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3323479	0.88	PIK3CA (0.42)	ALDH1A1CYP1A2CYP3A4CYP2D6CLK4
	SCHEMBL3318951	0.87	PIK3CA (0.47)	ALDH1A1CYP1A2CYP3A4CYP2D6CLK4
	SCHEMBL3321755	0.86	HRH3 (0.47)	ALDH1A1CYP1A2CYP3A4CYP2D6CLK4
	SCHEMBL3324981	0.86	TSHR (0.41)	ALDH1A1CYP1A2CYP3A4CYP2D6CLK4
	SCHEMBL3322417	0.85	HRH3 (0.49)	ALDH1A1CYP1A2CYP3A4CYP2D6CLK4
	SCHEMBL3320637	0.85	HRH3 (0.49)	ALDH1A1CYP1A2CYP3A4CYP2D6CLK4
	SCHEMBL3324511	0.85	NMT1 (0.43)	ALDH1A1NMT1MAPT
	SCHEMBL3321682	0.85	NPY5R (0.39)	ALDH1A1CYP1A2CYP3A4CYP2D6CLK4
	SCHEMBL3320279	0.85	PIK3CA (0.48)	ALDH1A1LMNATSHRMEN1KMT2A
	SCHEMBL3320920	0.85	PIK3CA (0.48)	ALDH1A1NMT1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.