SCHEMBL3318951

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3323479	0.92	PIK3CA (0.42)	PIK3CAMTORALDH1A1POLBTP53
	SCHEMBL3324511	0.91	NMT1 (0.43)	PIK3CAMTORALDH1A1MAPTHTT
	SCHEMBL3320279	0.91	PIK3CA (0.48)	PIK3CAMTORALDH1A1POLBMAPT
	SCHEMBL3320920	0.91	PIK3CA (0.48)	PIK3CAMTORALDH1A1POLBMAPT
	SCHEMBL3326349	0.89	PIK3CA (0.51)	PIK3CAMTORALDH1A1HSD11B1POLB
	SCHEMBL3320615	0.89	KMT2A (0.48)	PIK3CAMTORALDH1A1HSD11B1POLB
	SCHEMBL3321769	0.89	L3MBTL1 (0.49)	PIK3CAMTORALDH1A1HSD11B1MAPT
	SCHEMBL3321556	0.89	L3MBTL1 (0.44)	PIK3CAMTORMAPTGAA
	SCHEMBL3319063	0.88	LMNA (0.47)	PIK3CAMTORALDH1A1HSD11B1POLB
	SCHEMBL3316840	0.87	ALDH1A1 (0.42)	ALDH1A1MAPTKDM4ELMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.