Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.31 |
| ▸ | GABRD | O14764 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21621641 | 1.00 | CHRNB2 (0.36) | CHRNB2CHRNB4CHRNA4CHRNA3CHRM1 | |
| SCHEMBL23974055 | 0.80 | CHRNB2 (0.33) | CHRNB2CHRNB4CHRNA4CHRNA3 | |
| SCHEMBL1320264 | 0.80 | CHRM1 (0.56) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL16586241 | 0.80 | CHRM1 (0.56) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL21621503 | 0.79 | CHRM1 (0.34) | CHRNB2CHRNB4CHRNA4CHRNA3CHRM1 | |
| SCHEMBL5044801 | 0.79 | CHRM1 (0.32) | CHRNB2CHRNB4CHRNA4CHRNA3CHRM1 | |
| SCHEMBL28376043 | 0.79 | CHRNB2 (0.37) | CHRNB2CHRNB4CHRNA4CHRNA3 | |
| SCHEMBL199041 | 0.79 | — | — | |
| SCHEMBL331728 | 0.79 | — | — | |
| SCHEMBL199040 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6432896-B1 | MIXTURE; CLEANING COMPOUND; HEAT RESISTANCE | KAO CORPORATION (JP) | 2002-08-13 | — | — | US | claimed |
| EP-3610849-B1 | METHOD FOR REMOVING KERATOTIC PLUGS | KAO CORP (JP) | 2025-09-17 | — | — | EP | disclosed |
| EP-3610848-B1 | SKIN CLEANSING COMPOSITION | KAO CORP (JP) | 2025-08-27 | — | — | EP | disclosed |
| EP-4023304-B1 | A KERATOTIC PLUG-REMOVING COMPOSITION | KAO CORP (JP) | 2025-08-27 | — | — | EP | disclosed |
| US-11975086-B2 | Method for removing keratotic plugs | KAO CORPORATION (JP) | 2024-05-07 | — | — | US | disclosed |
| EP-4269549-A2 | SKIN CLEANSING COMPOSITIONS | Kao Corporation (JP) | 2023-11-01 | — | — | EP | disclosed |
| EP-3610850-B1 | SKIN CLEANSING COMPOSITIONS | KAO CORP (JP) | 2023-10-25 | — | — | EP | disclosed |
| CN-116785188-A | Skin cleansing composition | 花王株式会社 | 2023-09-22 | — | — | CN | disclosed |
| CN-110520102-B | Skin cleansing composition | 花王株式会社 | 2023-08-22 | — | — | CN | disclosed |
| CN-110494120-B | Method for removing corner bolts | 花王株式会社 | 2023-07-18 | — | — | CN | disclosed |
| CN-110494119-A | Composition of skin cleanser | KAO CORP | 2019-11-22 | — | — | CN | disclosed |
| CN-110494120-A | The method for removing keratotic plug | KAO CORP | 2019-11-22 | — | — | CN | disclosed |
| CN-110418633-A | The method for removing keratotic plug | KAO CORP | 2019-11-05 | — | — | CN | disclosed |
| CN-1163575-C | Detergent composition | ������������ʽ���� | 2004-08-25 | — | — | CN | disclosed |
| EP-1043386-B1 | DETERGENT COMPOSITION | KAO CORP (JP) | 2004-05-12 | — | — | EP | disclosed |
| US-6551971-B2 | Cleaning compound for skin | KAO CORPORATION (JP) | 2003-04-22 | — | — | US | disclosed |
| US-20020119908-A1 | Detergent composition comprising an amphoteric surfactant system | KAO CORPORATION (JP) | 2002-08-29 | — | — | US | disclosed |
| US-6432896-B1 | MIXTURE; CLEANING COMPOUND; HEAT RESISTANCE | KAO CORPORATION (JP) | 2002-08-13 | — | — | US | disclosed |
| CN-1282365-A | Detergent composition | KAO CORP (JP) | 2001-01-31 | — | — | CN | disclosed |
| EP-1043386-A1 | DETERGENT COMPOSITION | Kao Corporation (JP) | 2000-10-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11975086-B2 | Method for removing keratotic plugs | PAM, MUC1, CUTA | CHRNB2 1134/4885CHRNB4 2060/4885CHRNA4 2460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.