Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.38 |
| ▸ | KDM5A | P29375 | 7/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.33 |
| ▸ | KDM4A | O75164 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726264 | 0.91 | CHRM2 (0.43) | LTA4HKDM4CKDM5ATHRATHRB | |
| SCHEMBL27972459 | 0.91 | LTA4H (0.42) | LTA4HKDM4CKDM5ACHRM2KMT2A | |
| SCHEMBL3319751 | 0.88 | KMT2A (0.41) | LTA4HTHRATHRBMAPTKMT2A | |
| SCHEMBL26495389 | 0.82 | KDM4C (0.50) | KDM4CKDM5AKDM5CKDM5BPHF8 | |
| SCHEMBL30074288 | 0.81 | LTA4H (0.47) | LTA4HKDM4CKDM5ACHRM2KMT2A | |
| Carbamic Acid SCHEMBL9587573 | 0.80 | MAPT (0.43) | KDM4CKDM5ATHRATHRBMAPT | |
| SCHEMBL8386761 | 0.80 | KDM5A (0.51) | KDM4CKDM5AKMT2AMEN1KDM5C | |
| SCHEMBL3316660 | 0.79 | KDM4C (0.47) | LTA4HKDM4CKDM5AKMT2AMEN1 | |
| SCHEMBL29641947 | 0.78 | S1PR2 (0.53) | KDM4CKDM5AKMT2AMEN1KDM5C | |
| SCHEMBL29641969 | 0.78 | S1PR2 (0.53) | KDM4CKDM5AKMT2AMEN1KDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100104659-A1 | BENZOPYRANOPYRAZOLES | 4SC AG (DE) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100104659-A1 | BENZOPYRANOPYRAZOLES | BAX, BCL2, BAD | LTA4H 3282/4885KDM4C 2767/4885KDM5A 3033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.