Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 10/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21351670 | 0.92 | POLB (0.42) | MLYCDACHEMAPTNPC1RAB9A | |
| SCHEMBL16432869 | 0.92 | POLB (0.42) | MLYCDACHEMAPTNPC1RAB9A | |
| SCHEMBL20999602 | 0.84 | MAPT (0.40) | ACHEMAPTNPC1RAB9AKDM4E | |
| SCHEMBL2605872 | 0.84 | MAPT (0.37) | MAPTNPC1RAB9AKDM4EMAPK1 | |
| SCHEMBL15357901 | 0.84 | RAB9A (0.41) | MAPTNPC1RAB9AKDM4EMAPK1 | |
| SCHEMBL18556273 | 0.84 | MAPT (0.40) | ACHEMAPTNPC1RAB9AKDM4E | |
| SCHEMBL16544008 | 0.80 | POLB (0.43) | MAPTPOLBAPEX1HTTTDP1 | |
| SCHEMBL16432867 | 0.80 | MLYCD (0.41) | MLYCDMAPTNPC1RAB9AKDM4E | |
| SCHEMBL2602717 | 0.80 | MMP14 (0.47) | MAPTNPC1RAB9AKDM4EMAPK1 | |
| SCHEMBL6932967 | 0.80 | MMP14 (0.47) | MAPTNPC1RAB9AKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220259593-A1 | CONTROL OF MAMMALIAN GENE DOSAGE USING CRISPR | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-08-18 | — | — | US | disclosed |
| US-20100105076-A1 | ANALYSIS KIT COMPRISING AT LEAST TWO MOLECULARLY IMPRINTED POLYMERS AND AT LEAST ONE MARKER, AND METHOD OF ANALYSIS USING SAME | POLYINTELL (FR) | 2010-04-29 | — | — | US | disclosed |
| EP-2125195-A2 | ANALYSIS KIT COMPRISING AT LEAST TWO MOLECULARLY IMPRINTED POLYMERS AND AT LEAST ONE MARKER, AND METHOD OF ANALYSIS USING SAME | Polyintell (FR) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008132384-A2 | ANALYSIS KIT COMPRISING AT LEAST TWO MOLECULARLY IMPRINTED POLYMERS AND AT LEAST ONE MARKER, AND METHOD OF ANALYSIS USING SAME | POLYINTELL (FR) | 2008-11-06 | — | — | WO | disclosed |