Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27737881 | 1.00 | ALDH1A1 (0.44) | ALDH1A1FABP4RENCYP3A4HSD17B2 | |
| SCHEMBL971537 | 1.00 | ALDH1A1 (0.44) | ALDH1A1FABP4RENCYP3A4HSD17B2 | |
| SCHEMBL3317847 | 1.00 | ALDH1A1 (0.44) | ALDH1A1FABP4RENCYP3A4HSD17B2 | |
| SCHEMBL971535 | 1.00 | ALDH1A1 (0.44) | ALDH1A1FABP4RENCYP3A4HSD17B2 | |
| SCHEMBL21928893 | 0.88 | ALDH1A1 (0.54) | ALDH1A1FABP4L3MBTL1KDM4E | |
| SCHEMBL21926398 | 0.88 | ALDH1A1 (0.54) | ALDH1A1FABP4L3MBTL1KDM4E | |
| SCHEMBL21926852 | 0.88 | ALDH1A1 (0.54) | ALDH1A1FABP4L3MBTL1KDM4E | |
| SCHEMBL23365129 | 0.87 | HSD17B2 (0.46) | HSD17B2DPP4DPP7OPRM1OPRD1 | |
| SCHEMBL5508506 | 0.85 | CHRM3 (0.46) | CYP3A4CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL5508508 | 0.85 | CHRM3 (0.46) | CYP3A4CACNA2D1CACNA1BCACNB1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100010228-A1 | PROCESS FOR THE ASYMMETRIC REDUCTION OF 3-BENZOYLPIPERIDINES | VITAE PHARMACEUTICALS, INC. (US) | 2010-01-14 | — | — | US | claimed |
| US-20100010228-A1 | PROCESS FOR THE ASYMMETRIC REDUCTION OF 3-BENZOYLPIPERIDINES | VITAE PHARMACEUTICALS, INC. (US) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100010228-A1 | PROCESS FOR THE ASYMMETRIC REDUCTION OF 3-BENZOYLPIPERIDINES | QDPR, ADH5, GABARAP | ALDH1A1 151/4885FABP4 4232/4885REN 169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.