SCHEMBL3318944

SCHEMBL3318944

CC(C)(O)c1ccccc1[SiH3]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
TSHR P16473 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP3A4 P08684 1/20 0.38
CYP2C19 P33261 1/20 0.38
CA2 P00918 1/20 0.37
HSD11B1 P28845 1/20 0.35
CASR P41180 2/20 0.33
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32
PGR P06401 1/20 0.31
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
HSP90AA1 P07900 1/20 0.30
HSP90AB1 P08238 1/20 0.30
HSP90B1 P14625 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29506834 0.81 ALDH1A1 (0.50) ALDH1A1TSHRTDP1CYP3A4CYP2C19
SCHEMBL2059781 0.81 ALDH1A1 (0.50) ALDH1A1TSHRTDP1CYP3A4CYP2C19
SCHEMBL6326256 0.79 ALDH1A1 (0.50) ALDH1A1TSHRTDP1CYP2C19CA2
SCHEMBL18802732 0.74 ALDH1A1 (0.44) ALDH1A1TSHRTDP1CYP3A4CYP2C19
SCHEMBL17029229 0.74 ALDH1A1 (0.56) ALDH1A1TSHRTDP1CYP3A4CYP2C19
SCHEMBL18802707 0.74 ALDH1A1 (0.44) ALDH1A1TSHRTDP1CYP3A4CYP2C19
SCHEMBL796229 0.72 GABRA1 (0.48) ALDH1A1TSHRTDP1CYP3A4CYP2C19
SCHEMBL548642 0.72 ALDH1A1 (0.68) ALDH1A1TSHRTDP1CYP3A4CYP2C19
SCHEMBL30368089 0.72 ALDH1A1 (0.68) ALDH1A1TSHRTDP1CYP3A4CYP2C19
SCHEMBL30471342 0.72 GABRA1 (0.48) ALDH1A1TSHRTDP1CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021044921-A1 CONJUGATED DIENE POLYMER, METHOD FOR PRODUCING CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER COMPOSITION, AND RUBBER COMPOSITION 旭化成株式会社 2021-03-11 WO disclosed
US-8460069-B2 Lens holder HOYA CORPORATION (JP) 2013-06-11 US disclosed
US-8216024-B2 Spectacle lens edging method HOYA CORPORATION (JP) 2012-07-10 US disclosed
EP-2140971-B1 LENS HOLDER HOYA CORP (JP) 2012-05-23 EP disclosed
US-20100112915-A1 LENS HOLDER HOYA CORPORATION (JP) 2010-05-06 US disclosed
US-20100105293-A1 SPECTACLE LENS EDGING METHOD HOYA CORPORATION (JP) 2010-04-29 US disclosed
EP-2140971-A1 LENS HOLDER Hoya Corporation (JP) 2010-01-06 EP disclosed
EP-2138269-A1 METHOD FOR EDGING LENS OF GLASSES Hoya Corporation (JP) 2009-12-30 EP disclosed
US-7318959-B2 Optical element having antireflection film HOYA CORPORATION (JP) 2008-01-15 US disclosed
EP-1433809-B1 Optical member having antireflection film HOYA CORP (JP) 2006-09-20 EP disclosed
US-20040146723-A1 Optical element having antireflection film HOYA CORPORATION (JP) 2004-07-29 US disclosed
EP-1433809-A1 Optical member having antireflection film HOYA CORPORATION (JP) 2004-06-30 EP disclosed