Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5181416 | 0.84 | MAPT (0.56) | MAPTCYP3A4TSHRMAPK1SLC6A4 | |
| SCHEMBL3317596 | 0.83 | CYP3A4 (0.49) | CYP3A4TSHRMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3322836 | 0.81 | RAB9A (0.45) | MAPTCYP3A4TSHRMAPK1ALDH1A1 | |
| SCHEMBL5178315 | 0.81 | NPC1 (0.48) | MAPTCYP3A4TSHRMAPK1ALDH1A1 | |
| SCHEMBL22966282 | 0.80 | MAPT (0.57) | MAPTCYP3A4TSHRMAPK1SLC6A2 | |
| SCHEMBL28439534 | 0.79 | MAPT (0.60) | MAPTCYP3A4TSHRMAPK1SLC6A2 | |
| SCHEMBL47039 | 0.79 | MAPT (0.43) | MAPTMAPK1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9860036 | 0.79 | ALDH1A1 (0.45) | MAPTTSHRMAPK1SLC6A2SLC6A4 | |
| SCHEMBL9516991 | 0.79 | ALDH1A1 (0.46) | MAPTCYP3A4TSHRMAPK1SLC6A4 | |
| SCHEMBL31556301 | 0.78 | MAPT (0.55) | MAPTTSHRALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748662-B2 | 4-cycloalkyl or 4-aryl substituted phenoxyphenylamidines and use thereof as fungicides | BAYER CROPSCIENCE AG (DE) | 2014-06-10 | — | — | US | disclosed |
| US-20130012742-A1 | 4-CYCLOALKYL OR 4-SUBSTITUTED PHENOXYPHENYLAMIDINES AND USE THEREOF AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2013-01-10 | — | — | US | disclosed |
| US-8299302-B2 | 4-Cycloalkyl or 4-substituted phenoxyphenylamidines and use thereof as fungicides | BAYER CROPSCIENCE AG (DE) | 2012-10-30 | — | — | US | disclosed |
| US-20100120615-A1 | 4-CYCLOALKYL OR 4-SUBSTITUTED PHENOXYPHENYLAMIDINES AND USE THEREOF AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-05-13 | — | — | US | disclosed |
| EP-2120560-A1 | 4-CYCLOALKYL OR 4-ARYL SUBSTITUTED PHENOXYPHENYLAMIDINES AND USE THEREOF AS FUNGICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008110315-A1 | 4-CYCLOALKYL OR 4-ARYL SUBSTITUTED PHENOXYPHENYLAMIDINES AND USE TEHROF AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-09-18 | — | — | WO | disclosed |
| EP-1969934-A1 | 4-cycloalkyl or 4-aryl substituted phenoxy phenylamidines and their use as fungicides | Bayer CropScience AG (DE) | 2008-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120615-A1 | 4-CYCLOALKYL OR 4-SUBSTITUTED PHENOXYPHENYLAMIDINES AND USE THEREOF AS FUNGICIDES | DDT, CYP4B1, PAH | MAPT 3280/4885CYP3A4 7/4885TSHR 3047/4885 |
| US-20130012742-A1 | 4-CYCLOALKYL OR 4-SUBSTITUTED PHENOXYPHENYLAMIDINES AND USE THEREOF AS FUNGICIDES | DDT, CYP4B1, PAH | MAPT 3280/4885CYP3A4 7/4885TSHR 3047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.