SCHEMBL3317596

SCHEMBL3317596

Cc1cc(Oc2ccccc2)c(C)cc1N

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.49
CYP1A2 P05177 2/20 0.49
CYP2C9 P11712 2/20 0.49
CYP2C19 P33261 2/20 0.49
ALDH1A1 P00352 2/20 0.47
GAA P10253 1/20 0.47
TSHR P16473 2/20 0.43
MAPK1 P28482 1/20 0.43
MAOB P27338 1/20 0.42
MAOA P21397 1/20 0.42
LTA4H P09960 1/20 0.41
BRD4 O60885 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
NTRK1 P04629 1/20 0.39
IGF1R P08069 1/20 0.39
FGFR1 P11362 1/20 0.39
NTRK2 Q16620 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20262023 0.87 CYP1A2 (0.45) CYP3A4CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL16792756 0.84 CYP1A2 (0.45) CYP3A4CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL20521390 0.84 TTR (0.47) CYP3A4CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL21295558 0.84 CYP3A4 (0.49) CYP3A4CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL3319650 0.83 MAPT (0.48) CYP3A4CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL5181416 0.81 MAPT (0.56) CYP3A4CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL5179148 0.81 L3MBTL1 (0.55) CYP3A4CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL17466061 0.80 CYP1A2 (0.49) CYP3A4CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL5328536 0.80 AR (0.44) CYP3A4CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL28356598 0.80 ALDH1A1 (0.37) CYP3A4CYP1A2CYP2C9CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250214948-A1 TRIAZINE DERIVATIVES FOR TREATING DISEASES RELATING TO NEUROTROPHINS AlzeCure Pharma AB (SE) 2025-07-03 US disclosed
CN-111819172-B Triazine derivatives for the treatment of neurotrophin related diseases 阿泽克制药公司 2024-02-06 CN disclosed
EP-3759088-B1 TRIAZINE DERIVATIVES FOR TREATING DISEASES RELATING TO NEUROTROPHINS AlzeCure Pharma AB (SE) 2023-01-25 EP disclosed
US-20220306589-A1 TRIAZINE DERIVATIVES FOR TREATING DISEASES RELATING TO NEUROTROPHINS AlzeCure Pharma AB (SE) 2022-09-29 US disclosed
US-11352332-B2 Triazine derivatives for treating diseases relating to neurotrophins AlzeCure Pharma AB (SE) 2022-06-07 US disclosed
EP-3759088-A1 TRIAZINE DERIVATIVES FOR TREATING DISEASES RELATING TO NEUROTROPHINS Alzecure Pharma AB (SE) 2021-01-06 EP disclosed
US-20200399230-A1 TRIAZINE DERIVATIVES FOR TREATING DISEASES RELATING TO NEUROTROPHINS AlzeCure Pharma AB (SE) 2020-12-24 US disclosed
CN-111819172-A Triazine derivatives for the treatment of neurotrophin-related disorders 阿泽克制药公司 2020-10-23 CN disclosed
WO-2019162702-A1 TRIAZINE DERIVATIVES FOR TREATING DISEASES RELATING TO NEUROTROPHINS AlzeCure Pharma AB (SE) 2019-08-29 WO disclosed
EP-2136629-B1 PHENOXYPHENYLAMIDINES AS FUNGICIDES BAYER IP GMBH (DE) 2015-05-13 EP disclosed
US-8519003-B2 Phenoxyphenylamidines as fungicides BAYER CROPSCIENCE AG (DE) 2013-08-27 US disclosed
US-20100105552-A1 PHENOXYPHENYLAMIDINES AS FUNGICIDES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2010-04-29 US disclosed
EP-2136629-A1 PHENOXYPHENYLAMIDINES AS FUNGICIDES Bayer CropScience AG (DE) 2009-12-30 EP disclosed
WO-2008110313-A1 PHENOXYPHENYLAMIDINES AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2008-09-18 WO disclosed
EP-1969930-A1 Phenoxy phenylamidines and their use as fungicides Bayer CropScience AG (DE) 2008-09-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100105552-A1 PHENOXYPHENYLAMIDINES AS FUNGICIDES DDT, PAH, PFAS CYP3A4 18/4885CYP1A2 7/4885CYP2C9 13/4885
US-20220306589-A1 TRIAZINE DERIVATIVES FOR TREATING DISEASES RELATING TO NEUROTROPHINS NTRK2, BDNF, NGF CYP3A4 4531/4885CYP1A2 2565/4885CYP2C9 4852/4885
US-20250214948-A1 TRIAZINE DERIVATIVES FOR TREATING DISEASES RELATING TO NEUROTROPHINS NTRK2, BDNF, NGF CYP3A4 4531/4885CYP1A2 2565/4885CYP2C9 4852/4885
US-11352332-B2 Triazine derivatives for treating diseases relating to neurotrophins NTRK2, BDNF, NGF CYP3A4 4426/4885CYP1A2 2171/4885CYP2C9 4815/4885
US-20200399230-A1 TRIAZINE DERIVATIVES FOR TREATING DISEASES RELATING TO NEUROTROPHINS NTRK2, BDNF, NGF CYP3A4 4426/4885CYP1A2 2171/4885CYP2C9 4815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.