Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 6/20 | 0.46 |
| ▸ | CA9 | Q16790 | 6/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3321274 | 0.98 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL29850978 | 0.95 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL29445883 | 0.94 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL1552674 | 0.94 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL30828778 | 0.92 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL4245707 | 0.91 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL5888957 | 0.90 | MAP2K1 (0.49) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL29987184 | 0.88 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL29470083 | 0.88 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL29851098 | 0.86 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119055662-A | Application of ginkgolic acid in preparation of medicine for treating acute lung injury | 中国中医科学院中药研究所 | 2024-12-03 | — | — | CN | disclosed |
| US-20100068150-A1 | Selective Caspase Inhibitors | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2010-03-18 | — | — | US | disclosed |
| US-20100016228-A1 | TRUNCATED BARD1 PROTEIN, AND ITS DIAGNOSTIC AND THERAPEUTIC USES | AYANDA BIOSYSTEMS SA (CH) | 2010-01-21 | — | — | US | disclosed |
| US-7566764-B2 | Truncated BARD1 protein, and its diagnostic and therapeutic uses | AYANDA BIOSYSTEMS SA (CH) | 2009-07-28 | — | — | US | disclosed |
| US-20040234959-A1 | Truncated bard1 protein, and its diagnostic and therapeutic uses | EUROGOLD LIMITED (AU) | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100068150-A1 | Selective Caspase Inhibitors | CASP14, MLKL, CASP7 | KDM4E 2814/4885ALDH1A1 3882/4885HPGD 3836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.