SCHEMBL332010

SCHEMBL332010

COC(=O)C=[N+]=[N-]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrogen SCHEMBL29248631 0.95
Dioxane SCHEMBL28861396 0.87 HCAR2 (0.37)
SCHEMBL13108979 0.74
SCHEMBL9703507 0.72
SCHEMBL42660 0.72 MEN1 (0.38)
SCHEMBL4412 0.72
SCHEMBL28808082 0.69
SCHEMBL294874 0.69
Alcohol SCHEMBL28357108 0.69 HCAR2 (0.43)
SCHEMBL31463337 0.67 CTSK (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 317 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250092008-A1 PROCESS FOR MAKING AN EP4 ANTAGONIST ONO PHARMACEUTICAL CO., LTD. (JP) 2025-03-20 US claimed
CN-118652168-A Preparation method of 2, 3-tetramethyl cyclopropane carboxylic acid 大连凯飞化学股份有限公司 2024-09-17 CN claimed
EP-4384509-A1 PROCESS FOR MAKING AN EP4 ANTAGONIST ONO Pharmaceutical Co., Ltd. (JP) 2024-06-19 EP claimed
CN-118164852-A Method for synthesizing cyclopropane carboxylic ester by using channel reactor 江苏优嘉植物保护有限公司 2024-06-11 CN claimed
CN-117534564-A Method for synthesizing alpha-acyloxy-beta, gamma-unsaturated ester and derivative thereof 常州大学 2024-02-09 CN claimed
WO-2023017813-A1 PROCESS FOR MAKING AN EP4 ANTAGONIST ONO PHARMACEUTICAL CO., LTD. (JP) 2023-02-16 WO claimed
CN-115368238-A Novel method for synthesizing trans-olefin by using alpha-aryl diazoacetic acid methyl ester induced by visible light 桂林理工大学 2022-11-22 CN claimed
CN-115028570-A Preparation method of (1R, 2S, 5S) -6, 6-dimethyl-3-azabicyclo [3, 1, 0] hexyl-2-carboxylate 浙江新和成股份有限公司 2022-09-09 CN claimed
CN-106831764-B A kind of Indoli zine derivatives and preparation method thereof 苏州大学 2018-11-02 CN claimed
CN-106831764-A A kind of Indoli zine derivatives and preparation method thereof 苏州大学 2017-06-13 CN claimed
CN-1218714-A Catalyst for olefine cyclopropaning reaction DALIAN CHEMICAL PHYSICS INST (CN) 1999-06-09 CN claimed
CN-1191774-A Catalyst for cyclopropanization of 1,1-dichloro-4-methyl-1,3-pentylene DALIAN CHEMICAL PHYSICS INST (CN) 1998-09-02 CN claimed
CN-1191773-A Catalyst for cyclopropanization of 1,1-dichloro-4-methyl-1,3-pentylene and its application DALIAN CHEMICAL PHYSICS INST (CN) 1998-09-02 CN claimed
EP-0594608-B1 CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS RES CORP TECHNOLOGIES INC (US) 1997-10-15 EP claimed
EP-0594608-A1 CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS. RES CORP TECHNOLOGIES INC (US) 1994-05-04 EP claimed
US-5296595-A Metal complexes with bridging ligands RESEARCH CORPORATION TECHNOLOGIES (US) 1994-03-22 US claimed
EP-0594608-A4 CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS. RES CORP TECHNOLOGIES INC (US) 1993-03-15 EP claimed
US-5175311-A Reacting olefin with carbene precursor RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1992-12-29 US claimed
WO-1991014672-A1 CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1991-10-03 WO claimed
US-4703033-A IMMUNOSUPPRESSIVE AGENTS SANDOZ LTD. (CH) 1987-10-27 US claimed