SCHEMBL42660

SCHEMBL42660

CC(C)(C)OC(=O)C=[N+]=[N-]

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 1/20 0.38
HIF1A Q16665 1/20 0.38
DGAT1 O75907 1/20 0.33
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL334886 0.80 ALDH1A1 (0.35) MEN1ALDH1A1HTTKMT2AHIF1A
SCHEMBL8080248 0.80 DGAT1 (0.36) DGAT1
SCHEMBL16828345 0.79 ALDH1A1 (0.34) MEN1ALDH1A1HTTKMT2AHIF1A
SCHEMBL20184262 0.78
SCHEMBL8843634 0.77 MEN1 (0.36) MEN1ALDH1A1HTTKMT2AHIF1A
SCHEMBL334562 0.73 MAPK1 (0.32) MEN1ALDH1A1HTTKMT2AHIF1A
SCHEMBL16828348 0.73 ALDH1A1 (0.36) MEN1ALDH1A1HTTKMT2AHIF1A
SCHEMBL7105703 0.73 ALDH1A1 (0.33) MEN1ALDH1A1HTTKMT2AHIF1A
SCHEMBL332010 0.72
SCHEMBL11007623 0.72 MEN1 (0.30) MEN1ALDH1A1HTTKMT2AHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1091 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12473688-B2 Carbene co-grafting modified fabric, preparation and application thereof SOOCHOW UNIVERSITY (CN) 2025-11-18 US claimed
US-20250092008-A1 PROCESS FOR MAKING AN EP4 ANTAGONIST ONO PHARMACEUTICAL CO., LTD. (JP) 2025-03-20 US claimed
CN-118930436-A Method for catalyzing coupling reaction of nitro compound and diazo compound by using corrinyl ring-containing small molecular compound 北京化工大学 2024-11-12 CN claimed
US-20240344265-A1 CARBENE CO-GRAFTING MODIFIED FABRIC, PREPARATION AND APPLICATION THEREOF SOOCHOW UNIVERSITY (CN) 2024-10-17 US claimed
EP-4384509-A1 PROCESS FOR MAKING AN EP4 ANTAGONIST ONO Pharmaceutical Co., Ltd. (JP) 2024-06-19 EP claimed
CN-117265554-A Method for preparing thioester derivative by electrocatalytic reaction 江苏中利集团股份有限公司 2023-12-22 CN claimed
CN-117105874-A Preparation method of N-alkoxyl acyl methyl substituted-1, 2, 3-triazole 曲阜师范大学 2023-11-24 CN claimed
WO-2023155368-A1 CARBENE CO-GRAFTED MODIFIED FABRIC, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 苏州大学 2023-08-24 WO claimed
WO-2023017813-A1 PROCESS FOR MAKING AN EP4 ANTAGONIST ONO PHARMACEUTICAL CO., LTD. (JP) 2023-02-16 WO claimed
CN-114481608-B Carbene co-grafting modified fabric and preparation method and application thereof 苏州大学 2022-12-30 CN claimed
US-20030073849-A1 Cyclopropylindole derivatives as selective serotonin reuptake inhibitors BRISTOL-MYERS SQUIBB COMPANY 2003-04-17 US claimed
US-20030013696-A1 Methods and compositions for photo-cross linking photoactive compounds to target tissue BRITISH COLUMBIA, UNIVERSITY OF, THE (CA) 2003-01-16 US claimed
WO-2002079152-A1 CYCLOPROPYLINDOLE DERIVATIVES AS SELECTIVE SEROTONIN REUPTAKE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2002-10-10 WO claimed
WO-2002076453-A1 METHODS AND COMPOSITIONS FOR PHOTO-CROSS LINKING PHOTOACTIVE COMPOUNDS TO TARGET TISSUE THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2002-10-03 WO claimed
EP-0594608-B1 CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS RES CORP TECHNOLOGIES INC (US) 1997-10-15 EP claimed
EP-0594608-A1 CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS. RES CORP TECHNOLOGIES INC (US) 1994-05-04 EP claimed
US-5296595-A Metal complexes with bridging ligands RESEARCH CORPORATION TECHNOLOGIES (US) 1994-03-22 US claimed
EP-0594608-A4 CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS. RES CORP TECHNOLOGIES INC (US) 1993-03-15 EP claimed
US-5175311-A Reacting olefin with carbene precursor RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1992-12-29 US claimed
WO-1991014672-A1 CHIRAL CATALYSTS FOR ENANTIOSELECTIVE SYNTHESIS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1991-10-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030073849-A1 Cyclopropylindole derivatives as selective serotonin reuptake inhibitors HTR5A, HTR1A, HTR2C MEN1 3485/4885ALDH1A1 961/4885HTT 763/4885
US-20250092008-A1 PROCESS FOR MAKING AN EP4 ANTAGONIST PTGER4, LTB4R2, EPB41 MEN1 4691/4885ALDH1A1 1405/4885HTT 4791/4885
US-20030013696-A1 Methods and compositions for photo-cross linking photoactive compounds to target tissue LCP1, PPOX, TYR MEN1 4224/4885ALDH1A1 542/4885HTT 2959/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.