⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1941718 | 0.74 | — | — | |
| SCHEMBL332010 | 0.72 | — | — | |
| SCHEMBL299245 | 0.69 | — | — | |
| Nitrogen SCHEMBL29248631 | 0.69 | — | — | |
| SCHEMBL42660 | 0.67 | MEN1 (0.38) | — | |
| SCHEMBL4412 | 0.67 | — | — | |
| SCHEMBL13676302 | 0.67 | — | — | |
| SCHEMBL668937 | 0.67 | — | — | |
| SCHEMBL367403 | 0.65 | — | — | |
| SCHEMBL3145325 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4703033-A | IMMUNOSUPPRESSIVE AGENTS | SANDOZ LTD. (CH) | 1987-10-27 | — | — | US | claimed |
| EP-0194972-B1 | NOVEL CYCLOSPORINS | SANDOZ AG (CH) | 1992-07-29 | — | — | EP | disclosed |
| US-4771122-A | IMMUNOSUPPRESIVE, ANTIPARASITIC, ANTIINFLAMMATORY | SANDOZ LTD. (CH) | 1988-09-13 | — | — | US | disclosed |
| US-4703033-A | IMMUNOSUPPRESSIVE AGENTS | SANDOZ LTD. (CH) | 1987-10-27 | — | — | US | disclosed |
| EP-0194972-A2 | Novel cyclosporins | SANDOZ AG (CH) | 1986-09-17 | — | — | EP | disclosed |