Trolamine

Trolamine

SCHEMBL3320439

OCC[NH+](CCO)CCO.c1ccc([B-](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.37
TSHR P16473 1/20 0.35
ALDH1A1 P00352 4/20 0.33
RECQL P46063 1/20 0.33
BACE1 P56817 1/20 0.32
HSD17B10 Q99714 2/20 0.32
LMNA P02545 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
BCL2L1 Q07817 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL139187 0.79 ALDH1A1 (0.34) ALDH1A1HSD17B10LMNANPSR1HPGD
SCHEMBL143787 0.76 TSHR (0.35) TDP1TSHRALDH1A1HSD17B10LMNA
Benzene SCHEMBL31091106 0.76 ALDH1A1 (0.50) TDP1TSHRALDH1A1RECQLBACE1
SCHEMBL11707018 0.76 ALDH1A1 (0.50) TDP1TSHRALDH1A1RECQLBACE1
SCHEMBL143876 0.76 ALDH1A1 (0.50) TDP1TSHRALDH1A1RECQLBACE1
Alcohol SCHEMBL28542828 0.75 ALDH1A1 (0.40) TDP1TSHRALDH1A1BACE1HSD17B10
Trolamine SCHEMBL149116 0.74 KDM4E (0.42) TDP1TSHRALDH1A1RECQLHSD17B10
SCHEMBL8849836 0.74 LTA4H (0.35) TSHR
SCHEMBL31697703 0.73 ALDH1A1 (0.41) TDP1TSHRALDH1A1RECQLBACE1
SCHEMBL31599226 0.73 ALDH1A1 (0.41) TSHRALDH1A1RECQLHSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100120941-A1 ADHESIVE AGENT FOR ADHESION BETWEEN ALGINATE IMPRESSION MATERIAL FOR DENTAL APPLICATIONS AND IMPRESSION TRAY, AND KIT COMPRISING THE ADHESIVE AGENT TOKUYAMA DENTAL CORPORATION (JP) 2010-05-13 US disclosed
EP-2127631-A1 ADHESIVE AGENT FOR ADHESION BETWEEN ALGINATE IMPRESSION MATERIAL FOR DENTAL APPLICATIONS AND IMPRESSION TRAY, AND KIT COMPRISING THE ADHESIVE AGENT Tokuyama Dental Corporation (JP) 2009-12-02 EP disclosed
JP-2006056844-A ONE-PASTE TYPE PHOTOCURABLE DENTAL COMPOSITE REPAIRING MATERIAL TOKUYAMA CORP 2006-03-02 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100120941-A1 ADHESIVE AGENT FOR ADHESION BETWEEN ALGINATE IMPRESSION MATERIAL FOR DENTAL APPLICATIONS AND IMPRESSION TRAY, AND KIT COMPRISING THE ADHESIVE AGENT ICAM1, ITGB8, TRA2B TDP1 2135/4885TSHR 3790/4885ALDH1A1 2057/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.