Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | AGXT | P21549 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11288839 | 0.82 | CYP1A2 (0.68) | CYP1A2CYP2A6TAAR1IDO1KCNH2 | |
| SCHEMBL143961 | 0.82 | CYP1A2 (0.68) | CYP1A2CYP2A6TAAR1IDO1KCNH2 | |
| SCHEMBL27961265 | 0.79 | KMT2A (0.49) | TDP1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL6546754 | 0.77 | IGF1R (0.64) | CYP1A2CYP2A6TAAR1IDO1KCNH2 | |
| SCHEMBL6546878 | 0.77 | CYP1A2 (0.62) | CYP1A2CYP2A6TAAR1IDO1KCNH2 | |
| SCHEMBL6426239 | 0.77 | — | — | |
| SCHEMBL19263826 | 0.74 | CYP1A2 (0.59) | CYP1A2CYP2A6TAAR1IDO1KCNH2 | |
| SCHEMBL10571160 | 0.74 | IGF1R (0.61) | CYP1A2CYP2A6TAAR1IDO1KCNH2 | |
| SCHEMBL10452106 | 0.74 | CYP1A2 (0.59) | CYP1A2CYP2A6TAAR1IDO1KCNH2 | |
| SCHEMBL5493944 | 0.74 | CYP1A2 (0.59) | CYP1A2CYP2A6TAAR1IDO1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017082924-A1 | PEPTIDE AND PEPTIDE MIMETIC BINDING ANTAGONISTS OF POLO-LIKE KINASE 1 POLO BOX DOMAIN AND METHODS OF USE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 2017-05-18 | — | — | WO | disclosed |
| US-8572842-B2 | Method for thermally enhancing injection of power cables | NOVINIUM, INC. (US) | 2013-11-05 | — | — | US | disclosed |
| WO-2013123592-A1 | OPTICAL FILTER WITH LIGHT SOURCE | SWITCH MATERIALS INC. (CA) | 2013-08-29 | — | — | WO | disclosed |
| CN-103154095-A | Cyclosiloxane-substituted polysiloxane compounds, compositions containing the same, and methods of use thereof | BIOFILM IP LLC | 2013-06-12 | — | — | CN | disclosed |
| CN-101394747-B | Water-stabilised antimicrobial organosilane products, compositions, and methods for using the same | VITEC SPECIALITY CHEMICALS LTD | 2013-04-24 | — | — | CN | disclosed |
| US-20100122453-A1 | THERMALLY ENHANCED POWER CABLE REJUVENATION | TECHNOLOGY RESEARCH, LLC | 2010-05-20 | — | — | US | disclosed |
| CN-101394747-A | Water-stabilised antimicrobial organosilane products, compositions, and methods for using the same | VITEC SPECIALITY CHEMICALS LTD (GB) | 2009-03-25 | — | — | CN | disclosed |
| EP-0630933-B1 | A method of producing a semiconducting material | NIPPON OIL CO LTD (JP) | 1999-04-14 | — | — | EP | disclosed |
| EP-0630933-A2 | A method of producing a semiconducting material | NIPPON OIL CO. LTD. (JP) | 1994-12-28 | — | — | EP | disclosed |