Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SCN1A | P35498 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1784136 | 0.88 | TSHR (0.57) | LMNACYP1A2CYP2D6POLBSCN1A | |
| SCHEMBL443825 | 0.83 | ALDH1A1 (0.54) | LMNACYP1A2CYP2D6POLBSCN1A | |
| SCHEMBL8946971 | 0.82 | LMNA (0.51) | LMNACYP1A2CYP2D6POLBSCN1A | |
| SCHEMBL28279379 | 0.82 | LMNA (0.46) | LMNACYP1A2CYP2D6POLBSCN1A | |
| SCHEMBL2578004 | 0.81 | ALDH1A1 (0.62) | LMNACYP1A2CYP2D6POLBSCN1A | |
| SCHEMBL16366695 | 0.81 | ALDH1A1 (0.62) | LMNACYP1A2CYP2D6POLBSCN1A | |
| SCHEMBL14616015 | 0.80 | LMNA (0.52) | LMNACYP1A2CYP2D6POLBSCN1A | |
| Phenol SCHEMBL28543645 | 0.80 | CA12 (0.47) | LMNACYP1A2CYP2D6POLBSCN1A | |
| SCHEMBL2980323 | 0.80 | LMNA (0.55) | LMNACYP1A2CYP2D6POLBSCN1A | |
| SCHEMBL2982475 | 0.80 | LMNA (0.55) | LMNACYP1A2CYP2D6POLBSCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2388017-A2 | Catalytic radiofluorination | The General Hospital Corporation (US) | 2011-11-23 | — | — | EP | disclosed |