Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | STS | P08842 | 10/20 | 0.63 |
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | CA9 | Q16790 | 3/20 | 0.59 |
| ▸ | ESR1 | P03372 | 2/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.59 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.59 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.59 |
| ▸ | CA4 | P22748 | 1/20 | 0.59 |
| ▸ | CA6 | P23280 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691697 | 0.92 | HSD17B1 (0.74) | KDM4EALDH1A1HSD17B1LMNAMAPT | |
| SCHEMBL10134113 | 0.92 | HSD17B1 (0.74) | KDM4EALDH1A1HSD17B1LMNAMAPT | |
| SCHEMBL3324357 | 0.88 | KDM4E (0.65) | KDM4EALDH1A1HSD17B1LMNAMAPT | |
| SCHEMBL11672003 | 0.88 | HSD17B1 (0.74) | KDM4EALDH1A1HSD17B1LMNAMAPT | |
| SCHEMBL14044784 | 0.88 | HSD17B1 (0.74) | KDM4EALDH1A1HSD17B1LMNAMAPT | |
| Oleoylestrone SCHEMBL14803698 | 0.87 | KDM4E (0.62) | KDM4EALDH1A1HSD17B1LMNAMAPT | |
| Oleoylestrone SCHEMBL2669491 | 0.87 | KDM4E (0.62) | KDM4EALDH1A1HSD17B1LMNAMAPT | |
| Oleoylestrone SCHEMBL8069581 | 0.87 | KDM4E (0.62) | KDM4EALDH1A1HSD17B1LMNAMAPT | |
| SCHEMBL10037069 | 0.87 | KDM4E (0.62) | KDM4EALDH1A1HSD17B1LMNAMAPT | |
| Oleoylestrone SCHEMBL38079 | 0.87 | KDM4E (0.62) | KDM4EALDH1A1HSD17B1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100119595-A1 | Monounsaturated fatty acids and perhydrocyclopentanophenanthrene nucleus combination molecules, and their precursors, and the use of all of these as weight-loss agents | GIROUARD MICHAEL P | 2010-05-13 | — | — | US | disclosed |
| CN-101528730-A | Substituted imidazoles as bombesin receptor subtype-3 modulators | MERCK & CO INC (US) | 2009-09-09 | — | — | CN | disclosed |
| EP-1594481-A4 | MONOUNSATURATED FATTY ACIDS AND PERHYDROCYCLOPENTANOPHENANTHRENE NUCLEUS COMBINATION MOLECULES, AND THEIR PRECURSORS, AND THE USE OF ALL OF THESE AS WEIGHT-LOSS AGENTS | GIROUARD MICHAEL P (US) | 2006-05-17 | — | — | EP | disclosed |
| EP-1594481-A2 | MONOUNSATURATED FATTY ACIDS AND PERHYDROCYCLOPENTANOPHENANTHRENE NUCLEUS COMBINATION MOLECULES, AND THEIR PRECURSORS, AND THE USE OF ALL OF THESE AS WEIGHT-LOSS AGENTS | Girouard, Michael P. (US) | 2005-11-16 | — | — | EP | disclosed |
| US-20040157816-A1 | Monounsaturated fatty acids and perhydrocyclopentanophenanthrene nucleus combination molecules, and their precursors, and the use of all of these as weight-loss agents | GIROUARD MICHAEL P (US) | 2004-08-12 | — | — | US | disclosed |
| WO-2004045560-A2 | COMBINATION OF MONOUNSATURATED FATTY ACIDS AND ESTOGEN, AND THEIR USE | GIROUARD MICHAEL P (US) | 2004-06-03 | — | — | WO | disclosed |