Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3328928 | 0.88 | AGXT (0.38) | L3MBTL1CYP11B1CYP11B2CYP19A1SLC6A4 | |
| SCHEMBL18608433 | 0.85 | L3MBTL1 (0.38) | L3MBTL1CYP11B1CYP11B2CYP19A1SCN8A | |
| SCHEMBL3324430 | 0.84 | CYP11B1 (0.39) | L3MBTL1CYP11B1CYP11B2CYP19A1SCN8A | |
| SCHEMBL23648069 | 0.83 | L3MBTL1 (0.38) | L3MBTL1CYP11B1CYP11B2CYP19A1SCN8A | |
| SCHEMBL18608786 | 0.83 | KDM4E (0.45) | L3MBTL1SCN8ASCN10AHTTKDM4E | |
| SCHEMBL23648160 | 0.82 | SLC6A4 (0.45) | L3MBTL1CYP11B1CYP11B2CYP19A1SCN8A | |
| SCHEMBL4524498 | 0.81 | KDM4E (0.52) | L3MBTL1CYP11B1CYP11B2CYP19A1SCN8A | |
| SCHEMBL30549876 | 0.81 | KDM4E (0.52) | L3MBTL1CYP11B1CYP11B2CYP19A1SCN8A | |
| SCHEMBL3322824 | 0.81 | HTR2A (0.43) | L3MBTL1CYP11B1CYP11B2CYP19A1KMT2A | |
| SCHEMBL3324075 | 0.80 | TDP1 (0.46) | SCN8AHTTKDM4EKMT2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120784-A1 | NOVEL HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120784-A1 | NOVEL HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | SCD, SCD5, ACSL6 | L3MBTL1 2189/4885CYP11B1 121/4885CYP11B2 139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.