Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18608433 | 0.84 | L3MBTL1 (0.38) | SLC6A4KDM4EHTR2AKCNH2ALDH1A1 | |
| SCHEMBL18608786 | 0.82 | KDM4E (0.45) | TDP1SLC6A4KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL3322617 | 0.81 | TDP1 (0.42) | TDP1KDM4ESMN1; SMN2GAAALDH1A1 | |
| SCHEMBL30549876 | 0.80 | KDM4E (0.52) | SLC6A4RXFP1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL4524498 | 0.80 | KDM4E (0.52) | SLC6A4RXFP1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL3323835 | 0.80 | L3MBTL1 (0.37) | SLC6A4KDM4EHTR2AKCNH2CYP2D6 | |
| SCHEMBL3324430 | 0.80 | CYP11B1 (0.39) | SLC6A4KDM4EALDH1A1HTTKMT2A | |
| SCHEMBL23648069 | 0.80 | L3MBTL1 (0.38) | SLC6A4KDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL23648160 | 0.78 | SLC6A4 (0.45) | SLC6A4KDM4EALDH1A1CYP2C19HTT | |
| SCHEMBL4524912 | 0.78 | CYP2C19 (0.50) | RXFP1KDM4EALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120784-A1 | NOVEL HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120784-A1 | NOVEL HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | SCD, SCD5, ACSL6 | TDP1 3902/4885CACNA1B 2052/4885SLC6A4 2527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.