Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 6/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.39 |
| ▸ | SYK | P43405 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3324490 | 1.00 | CDK9 (0.41) | CDK9CCNT1IKBKBCHUKSCN9A | |
| SCHEMBL3325580 | 0.91 | SCN9A (0.46) | IKBKBCHUKSCN9ACTSSIRAK4 | |
| SCHEMBL3321355 | 0.91 | IKBKB (0.42) | IKBKBCHUKSCN9ACTSSIRAK4 | |
| SCHEMBL3321349 | 0.91 | IKBKB (0.42) | IKBKBCHUKSCN9ACTSSIRAK4 | |
| SCHEMBL3324507 | 0.91 | KDM1A (0.42) | IKBKBCHUKCTSSKITIRAK4 | |
| SCHEMBL3325572 | 0.91 | SCN9A (0.46) | IKBKBCHUKSCN9ACTSSIRAK4 | |
| SCHEMBL3329442 | 0.91 | KDM1A (0.42) | IKBKBCHUKCTSSKITIRAK4 | |
| SCHEMBL3325033 | 0.90 | CHRNB4 (0.45) | IKBKBCHUKKITCHRNB4CHRNA3 | |
| SCHEMBL3325029 | 0.90 | CHRNB4 (0.45) | IKBKBCHUKKITCHRNB4CHRNA3 | |
| SCHEMBL3324999 | 0.89 | SLC6A4 (0.45) | IKBKBCHUKCTSSKITIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120858-A1 | Piperidine Derivatives | PFIZER INC. | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120858-A1 | Piperidine Derivatives | P2RX5, P2RX7, P2RX1 | CDK9 2399/4885CCNT1 1046/4885IKBKB 1359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.