Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.84 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.76 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.76 |
| ▸ | MAPT | P10636 | 4/20 | 0.74 |
| ▸ | GAA | P10253 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL107219 | 0.92 | MAPT (0.71) | TRPV1ERCC1ERCC4MAPTGAA | |
| SCHEMBL26393857 | 0.92 | TRPV1 (1.00) | TRPV1ERCC1ERCC4MAPTGAA | |
| SCHEMBL31363209 | 0.90 | TRPV1 (0.68) | TRPV1ERCC1ERCC4MAPTGAA | |
| SCHEMBL2378518 | 0.90 | TRPV1 (0.68) | TRPV1ERCC1ERCC4MAPTGAA | |
| SCHEMBL13984316 | 0.89 | TRPV1 (0.67) | TRPV1ERCC1ERCC4MAPTGAA | |
| SCHEMBL109158 | 0.88 | MAPT (0.73) | TRPV1ERCC1ERCC4MAPTGAA | |
| SCHEMBL12246697 | 0.87 | MAPT (0.65) | TRPV1ERCC1ERCC4MAPTGAA | |
| SCHEMBL9444668 | 0.87 | ERCC1 (0.89) | TRPV1ERCC1ERCC4MAPTGAA | |
| SCHEMBL2186352 | 0.86 | HDAC2 (0.72) | GAAMEN1KMT2AKDM4ELMNA | |
| SCHEMBL7274719 | 0.86 | TRPV1 (0.79) | TRPV1ERCC1ERCC4MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100129436-A1 | SUBTANCES FOR THE PROTECTION OF CELLS AND/OR TISSUES | LOSEL RALF | 2010-05-27 | — | — | US | disclosed |
| US-20080167277-A1 | METHODS OF TREATING SKIN DISORDERS WITH CAFFEIC ACID ANALOGS | MOLECULIN, L.L.C. | 2008-07-10 | — | — | US | disclosed |
| US-20080167277-A1 | METHODS OF TREATING SKIN DISORDERS WITH CAFFEIC ACID ANALOGS | MOLECULIN, L.L.C. | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167277-A1 | METHODS OF TREATING SKIN DISORDERS WITH CAFFEIC ACID ANALOGS | CYP24A1, VDR, CYP2R1 | TRPV1 2766/4885ERCC1 979/4885ERCC4 635/4885 |
| US-20100129436-A1 | SUBTANCES FOR THE PROTECTION OF CELLS AND/OR TISSUES | CTSA, BCL2, BAX | TRPV1 3411/4885ERCC1 205/4885ERCC4 210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.