SCHEMBL3324717

SCHEMBL3324717

O=S(=O)(O)c1ccc(N=Nc2ccccc2)c(N(c2ccccc2)c2cccc3ccccc23)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SENP2 Q9HC62 3/20 0.49
▸ SENP1 Q9P0U3 3/20 0.49
▸ SENP3 Q9H4L4 2/20 0.49
▸ SUMO2 P61956 2/20 0.49
▸ SUMO1 P63165 2/20 0.49
▸ SENP7 Q9BQF6 2/20 0.49
▸ MAPK1 P28482 4/20 0.46
▸ KMT2A Q03164 3/20 0.46
▸ TDP1 Q9NUW8 3/20 0.46
▸ MAPT P10636 2/20 0.46
▸ GAA P10253 1/20 0.46
▸ POLB P06746 2/20 0.45
▸ CYP2D6 P10635 1/20 0.45
▸ CYP1A2 P05177 5/20 0.43
▸ HIF1A Q16665 3/20 0.43
▸ CYP2C9 P11712 2/20 0.43
▸ TSHR P16473 1/20 0.43
▸ PTPRA P18433 1/20 0.43
▸ PTPRB P23467 1/20 0.43
▸ CYP2C19 P33261 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1347625 0.83 POLB (0.58) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL3329717 0.74 SENP2 (0.49) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL3329715 0.74 SENP2 (0.49) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL14413250 0.73 CYP1A2 (0.65) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL28060655 0.73 POLB (0.50) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL27771162 0.71 POLB (0.66) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL30799092 0.70 SIGMAR1 (0.51) TDP1MAPTCYP2D6CYP1A2CYP2C9
SCHEMBL292397 0.70 SIGMAR1 (0.51) TDP1MAPTCYP2D6CYP1A2CYP2C9
SCHEMBL28711292 0.70 POLB (0.64) SENP2SENP1SENP3SUMO2SUMO1
SCHEMBL15274123 0.69 SENP2 (0.77) SENP2SENP1SENP3SUMO2SUMO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107984936-B Reusable writing material and preparation method thereof 吉林大学 2022-05-06 — — CN disclosed
US-20100119561-A1 Compositions Having a Performance Indicator AMCOL INTERNATIONAL CORPORATION (US) 2010-05-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100119561-A1 Compositions Having a Performance Indicator STRA6, EXOSC5, CD63 SENP2 1093/4885SENP1 1727/4885SENP3 1399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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