Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 7/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3326695 | 1.00 | LMNA (0.48) | LMNATDP1ALOX15MAPTAPP | |
| SCHEMBL5091931 | 0.88 | LMNA (0.45) | LMNATDP1ALOX15MAPTAKR1B10 | |
| SCHEMBL5091932 | 0.88 | LMNA (0.45) | LMNATDP1ALOX15MAPTAKR1B10 | |
| SCHEMBL14268793 | 0.88 | TDP1 (0.52) | LMNATDP1ALOX15MAPTPPARG | |
| SCHEMBL13478956 | 0.87 | TDP1 (0.47) | LMNATDP1ALOX15MAPTBACE1 | |
| SCHEMBL3332355 | 0.84 | ALOX15 (0.52) | LMNATDP1ALOX15MAPTAKR1B10 | |
| SCHEMBL3332354 | 0.84 | ALOX15 (0.52) | LMNATDP1ALOX15MAPTAKR1B10 | |
| SCHEMBL22293347 | 0.84 | LMNA (0.70) | LMNATDP1ALOX15MEN1KMT2A | |
| SCHEMBL3331573 | 0.82 | AKR1B10 (0.57) | LMNATDP1AKR1B10AKR1B1MEN1 | |
| SCHEMBL3331575 | 0.82 | AKR1B10 (0.57) | LMNATDP1AKR1B10AKR1B1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137627-A1 | 3-(2-Alkoxycarbonyloxy-Phenyl) Acrylic Acid Esters and Their Use as Precursors for the Delivery of Olfactory Compounds | GIVAUDAN SA (CH) | 2010-06-03 | — | — | US | disclosed |
| US-20080269102-A1 | 3-(2-Alkoxycarbonyloxy-Phenyl) Acrylic Acid Esters And Their Use As Precursors For The Delivery Of Olfactory Compounds | GIVAUDAN SA (CH) | 2008-10-30 | — | — | US | disclosed |
| EP-1725515-A1 | 3-(2-ALKOXYCARBONYLOXY-PHENYL)ACRYLIC ACID ESTERS AND THEIR USE AS PRECURSORS FOR THE DELIVERY OF OLFACTORY COMPOUNDS | Givaudan SA (CH) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005077881-A1 | 3-(2-ALKOXYCARBONYLOXY-PHENYL) ACRYLIC ACID ESTERS AND THEIR USE AS PRECURSORS FOR THE DELIVERY OF OLFACTORY COMPOUNDS | GIVAUDAN SA (CH) | 2005-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269102-A1 | 3-(2-Alkoxycarbonyloxy-Phenyl) Acrylic Acid Esters And Their Use As Precursors For The Delivery Of Olfactory Compounds | OR10J3, OR51E2, TAS2R43 | LMNA 3089/4885TDP1 4237/4885ALOX15 406/4885 |
| US-20100137627-A1 | 3-(2-Alkoxycarbonyloxy-Phenyl) Acrylic Acid Esters and Their Use as Precursors for the Delivery of Olfactory Compounds | OR10J3, OR51E2, TAS2R43 | LMNA 3089/4885TDP1 4237/4885ALOX15 406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.