Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3326769 | 0.99 | PYGL (0.40) | PYGLALDH1A1KDM4EGAAGLA | |
| SCHEMBL4146405 | 0.73 | TSHR (0.39) | ALDH1A1MTNR1AMTNR1BMEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL4146401 | 0.72 | TSHR (0.39) | ALDH1A1MTNR1AMTNR1BMEN1CYP1A2 | |
| SCHEMBL3326777 | 0.72 | PYGL (0.79) | PYGL | |
| SCHEMBL24650853 | 0.71 | EGFR (0.45) | F2MTNR1AMTNR1BEGFRMEN1 | |
| SCHEMBL4151106 | 0.71 | EGFR (0.45) | F2MTNR1AMTNR1BEGFRMEN1 | |
| SCHEMBL24650469 | 0.71 | PYGL (0.40) | PYGLF2MTNR1AMTNR1BEGFR | |
| Hydrochloric Acid SCHEMBL4151104 | 0.70 | EGFR (0.44) | F2EGFR | |
| SCHEMBL3327689 | 0.70 | DRD4 (0.39) | PYGLALDH1A1ATMF2MTNR1A | |
| SCHEMBL24650854 | 0.69 | F2 (0.43) | PYGLF2MTNR1AMTNR1BEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137397-A1 | Chemical Compounds | ASTRAZENECA AB (SE) | 2010-06-03 | — | — | US | disclosed |
| EP-1848721-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006082401-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2006-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137397-A1 | Chemical Compounds | PYGL, PYGM, GYS2 | PYGL 1/4885ALDH1A1 604/4885KDM4E 2362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.