⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209291 | 1.00 | — | — | |
| SCHEMBL10041943 | 1.00 | — | — | |
| SCHEMBL12810045 | 1.00 | — | — | |
| SCHEMBL10013538 | 1.00 | — | — | |
| SCHEMBL10231804 | 1.00 | — | — | |
| SCHEMBL7214312 | 1.00 | — | — | |
| SCHEMBL10013536 | 1.00 | — | — | |
| SCHEMBL3459775 | 1.00 | — | — | |
| SCHEMBL26823589 | 0.88 | LMNA (0.31) | — | |
| SCHEMBL13800901 | 0.86 | CA2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105037453-A | Preparation method of methyl-2,3-O-isopropylidene-5-deoxy-D-ribofuranoside | Qidong dongyue pharmaceutical co ltd | 2015-11-11 | — | — | CN | claimed |
| EP-0021231-B1 | PROCESS FOR THE PREPARATION OF 5'-DEOXY-5-FLUORO URIDINE AND INTERMEDIATES IN THIS PROCESS | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-10-05 | — | — | EP | claimed |
| US-11220524-B2 | Selective inhibitors of protein arginine methyltransferase 5 (PRMT5) | PRELUDE THERAPEUTICS INCORPORATED (US) | 2022-01-11 | — | — | US | disclosed |
| US-20210130388-A1 | SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASE 5 (PRMT5) | PRELUDE THERAPEUTICS, INCORPORATED | 2021-05-06 | — | — | US | disclosed |
| CN-110483593-A | A kind of preparation method of capecitabine intermediate | GUIZHOU YONGNUO FEITE BIOLOGICAL PHARMACEUTICAL CO LTD | 2019-11-22 | — | — | CN | disclosed |
| US-RE46144-E1 | Hydroxamic acid derivatives | PURDUE PHARMACEUTICAL PRODUCTS L.P. (US) | 2016-09-13 | — | — | US | disclosed |
| US-RE46144-E1 | Hydroxamic acid derivatives | PURDUE PHARMACEUTICAL PRODUCTS L.P. (US) | 2016-09-13 | — | — | US | disclosed |
| CN-102212095-B | The preparation method of capecitabine and intermediate thereof | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2016-03-30 | — | — | CN | disclosed |
| CN-103910773-B | The synthetic method of capecitabine impurity | NINGBO MENOVO PHARMACEUTICAL CO., LTD. (CN) | 2015-11-25 | — | — | CN | disclosed |
| CN-105037453-A | Preparation method of methyl-2,3-O-isopropylidene-5-deoxy-D-ribofuranoside | Qidong dongyue pharmaceutical co ltd | 2015-11-11 | — | — | CN | disclosed |
| CN-105037453-A | Preparation method of methyl-2,3-O-isopropylidene-5-deoxy-D-ribofuranoside | Qidong dongyue pharmaceutical co ltd | 2015-11-11 | — | — | CN | disclosed |
| US-20110224422-A1 | PREPARATION OF CAPECITABINE | DR. REDDY'S LABORATORIES LTD. (IN) | 2011-09-15 | — | — | US | disclosed |
| US-20100249395-A1 | METHODS FOR PREPARING CAPECITABINE AND BETA-ANOMER-RICH TRIALKYL CARBONATE COMPOUND USED THEREIN | HANMI PHARM. CO., LTD. (KR) | 2010-09-30 | — | — | US | disclosed |
| WO-2010065586-A2 | PREPARATION OF CAPECITABINE | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-06-10 | — | — | WO | disclosed |
| WO-2008117047-A1 | PYRAZOLO[3, 4-D]PYRIMIDINE DERIVATIVES AS ANTIBACTERIAL COMPOUNDS | ASTRAZENECA AB (SE) | 2008-10-02 | — | — | WO | disclosed |
| WO-1997033590-A1 | A METHOD OF TREATING DISORDERS RELATED TO CYTOKINES IN MAMMALS | NOVO NORDISK A/S (DK) | 1997-09-18 | — | — | WO | disclosed |
| WO-1997033591-A1 | A METHOD OF TREATING DISORDERS RELATED TO CYTOKINES IN MAMMALS | NOVO NORDISK A/S (DK) | 1997-09-18 | — | — | WO | disclosed |
| EP-0602478-B1 | Novel process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivatives | HOFFMANN LA ROCHE (CH) | 1996-07-31 | — | — | EP | disclosed |
| EP-0602478-A1 | Novel process for producing N4-acyl-5'-deoxy-5-fluorocytidine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1994-06-22 | — | — | EP | disclosed |
| EP-0021231-B1 | PROCESS FOR THE PREPARATION OF 5'-DEOXY-5-FLUORO URIDINE AND INTERMEDIATES IN THIS PROCESS | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-10-05 | — | — | EP | disclosed |